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Ilva Rupenthal

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Associate Professor and Director of the Buchanan Ocular Therapeutics Unit

University of Auckland

New Zealand

Research Interests

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About

Ilva Rupenthal is an Associate Professor at The University of Auckland, New Zealand. Her research focuses on diabetic retinopathy, ocular drug delivery systems, and the role of the NLRP3 inflammasome in chronic inflammation and autoimmune responses. She has contributed significantly to the understanding of extracellular vesicles in disease progression and the development of innovative drug delivery methods.

Recent Grants

Grant: Close

Novel treatments for diabetic vascular complications

Open Date: 2017-01-01

Close Date: 2019-01-01

Grant: Close

Stimuli-responsive ocular implants - More than meets the eye?

Open Date: 2014-01-01

Close Date: 2018-01-01

Grant: Close

Stimuli-responsive ocular implants - More than meets the eye?

Open Date: 2014-01-01

Close Date: 2018-01-01

Grant: Close

Reducing the treatment burden of ocular diseases

Open Date: 2013-01-01

Close Date: 2015-01-01

Grant: Close

Reducing the treatment burden of ocular diseases

Open Date: 2013-01-01

Close Date: 2015-01-01

Articles (23)

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2022

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NEW ZEALAND

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Rachael L. Niederer

University of Auckland

NEW ZEALAND

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Cornelia Keck

Philipps-Universität Marburg

GERMANY

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Simon Swift

Professor

University of Auckland

NEW ZEALAND

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Jennifer P. Craig

Professor

University of Auckland

NEW ZEALAND

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Ilva Rupenthal

Research Interests

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About

Recent Grants

Articles (23)

Influence of simulated tear flow on ocular penetration of transfersomes

A Cationic Block Co‐Polymer for Gene Delivery in the Posterior Segment of the Eye

Inhibiting the NLRP3 inflammasome pathway: An effective way to treat chronic inflammation in experimental autoimmune uveitis

Microsphere-loaded dual-response in situ gel for enhanced ocular drug delivery

Small Extracellular Vesicles Released from ARPE-19 Cells Grown under Diabetic Retinopathy Conditions Promote NLRP3 Inflammasome Activation

Characterisation of vitreous derived small extracellular vesicles in diabetic retinopathy

The NLRP3 inflammasome pathway contributes to chronic inflammation in experimental autoimmune uveitis

Design and delivery effect of prolonged-retention dexamethasone and tacrolimus microcrystals eye drops

Serum Albumin and Glycemic Variability Could Contribute to Diabetic Retinopathy Progression by Regulating Chronic Inflammatory Pathways

Mechanism of Ocular Penetration of Lipophilic Drugs from Lipophilic Vehicles

Future Therapeutics: Targeting the NLRP3 Inflammasome Pathway to Manage Diabetic Retinopathy Development and Progression

Development of transferosomes for topical ocular drug delivery of curcumin

Utilizing an Ex Vivo Skin Penetration Analysis Model for Predicting Ocular Drug Penetration: A Feasibility Study with Curcumin Formulations

Non-aqueous formulations in topical ocular drug delivery – a paradigm shift?

Preclinical characterization of water-free cyclosporine eye drops - factors impacting ocular penetration ex vivo and in vivo

Systemic Inflammasome Biomarkers as Predictors of Diabetic Retinopathy Progression: Evidence from a Pilot Study

Comprehensive Grading System for Experimental Autoimmune Uveitis in Mice

NLRP3 Inflammasome as a Potential Therapeutic Target in Dry Eye Disease

Orally Delivered Connexin43 Hemichannel Blocker, Tonabersat, Inhibits Vascular Breakdown and Inflammasome Activation in a Mouse Model of Diabetic Retinopathy

Extracellular Vesicles as Biomarkers and Therapeutics for Inflammatory Eye Diseases

Preparation and Characterisation of a Cyclodextrin-Complexed Mānuka Honey Microemulsion for Eyelid Application

Preclinical confirmation of UVC efficacy in treating infectious keratitis

Characterization of NLRP3 Inflammasome Activation in the Onset of Diabetic Retinopathy

Collaborators (9)

Rinki Murphy

Julie Lim

Ali Seyfoddin

Monica L. Acosta

Priyanka Agarwal

Rachael L. Niederer

Cornelia Keck

Simon Swift

Jennifer P. Craig

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