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In-Soo Yoon

Professor

Pusan National University

South Korea

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Research Interests

Pharmacology

100%

Pharmacotherapy

40%

Pharmacokinetic

70%

Cytochrome P450

40%

Drug Metabolism

30%

Inflammatory Bowel Disease

30%

In Vitro Studies

30%

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Articles15

Leukocyte Esterase-Activated Nanoconjugates Enables Precise Local Therapy of Ulcerative Colitis via Inflamed Tissue-Selective Drug Delivery

Year:

2025

Colon-Targeted β3-Adrenoceptor Agonist Mirabegron Enhances Anticolitic Potency of the Drug via Potentiating the Nrf2-HO-1 Pathway

Year:

2025

A simple and sensitive high‐performance liquid chromatographic method combined with fluorescence detection for bioanalysis of scopoletin in rat plasma: Application to a pharmacokinetic study

Year:

2024

Pharmacokinetics and extensive intestinal first-pass effects of apigenin and its active metabolite, apigenin-7-O-glucuronide, in rats

Year:

2024

A High-Performance Liquid Chromatography with Photodiode Array Detection Method for Simultaneous Determination of Three Compounds Isolated from Wikstroemia ganpi: Assessment of the Effects on Cytochrome P450-Mediated Metabolism In Vitro and In Vivo

Year:

2023

Investigation of the factors responsible for the low oral bioavailability of alizarin using a sensitive LC‐MS/MS method: In vitro, in situ, and in vivo evaluations

Year:

2023

N-Succinylaspartic-Acid-Conjugated Riluzole Is a Safe and Potent Colon-Targeted Prodrug of Riluzole against DNBS-Induced Rat Colitis

Year:

2023

Factors determining the oral absorption and systemic disposition of zeaxanthin in rats: in vitro, in situ, and in vivo evaluations

Year:

2022

Colon-Targeted Trans-Cinnamic Acid Ameliorates Rat Colitis by Activating GPR109A

Year:

2022

Determination of Leuprolide–Fatty Acid Conjugate in Rat Plasma Using LC-MS/MS and Its Pharmacokinetics after Subcutaneous Administration in Rats

Year:

2022

Dapsone Azo-Linked with Two Mesalazine Moieties Is a “Me-Better” Alternative to Sulfasalazine

Year:

2022

Development and application of a physiologically based pharmacokinetic model for entrectinib in rats and scale-up to humans: Route-dependent gut wall metabolism

Year:

2022

Eletrophilic Chemistry of Tranilast Is Involved in Its Anti-Colitic Activity via Nrf2-HO-1 Pathway Activation

Year:

2021

Novel Anti-Melanogenic Compounds, (Z)-5-(Substituted Benzylidene)-4-thioxothiazolidin-2-one Derivatives: In Vitro and In Silico Insights

Year:

2021

Assessment of Metabolic Interaction between Repaglinide and Quercetin via Mixed Inhibition in the Liver: In Vitro and In Vivo

Year:

2021

Collaborators5

Hyo-Eon Jin

Assistant professor

Ajou University

SOUTH KOREA

Eun Hee Lee

Associate Professor

Kangwon National University - Samcheok Campus

SOUTH KOREA

Hyung Ryong Moon

-

SOUTH KOREA

Heeyeong Cho

Yonsei University

SOUTH KOREA

Hwayoung Yun

-

SOUTH KOREA

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