Irene Min

Research scientist/ Associate Professor

Houston Methodist Research Institute

United States

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About

Dr. Irene Min is an Associate Professor at the Houston Methodist Research Institute in the United States. Her research primarily focuses on CAR T cell therapy, metastatic potential in pancreatic neuroendocrine tumors, and mechanisms of tumor resistance in various cancers. Recent publications highlight her work on enhancing targeting specificity in CAR T cells, understanding the JAK/STAT pathway's role in BRAF inhibitor resistance, and investigating the impact of environmental toxins on thyroid cells.

Articles (14)

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2024

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2024

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2024

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2023

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2023

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2023

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2022

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2022

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2022

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2021

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2021

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2020

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2020

Collaborators (4)

Juan Gonzalez-Valdivieso

Polytechnic University of Valencia

SPAIN

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David Kim

UNITED STATES

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Raymond Hall Yip Louie

University of New South Wales

AUSTRALIA

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Timothy Ullmann

Assistant Professor

Albany Medical College

UNITED STATES

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Irene Min

Research Interests

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Articles (14)

Affinity-tuned mesothelin CAR T cells demonstrate enhanced targeting specificity and reduced off-tumor toxicity

Developing a Predictive Model for Metastatic Potential in Pancreatic Neuroendocrine Tumor

Low-dose targeted radionuclide therapy synergizes with CAR T cells and enhances tumor response

Activation of the JAK/STAT Pathway Leads to BRAF Inhibitor Resistance in BRAFV600E Positive Thyroid Carcinoma.

Activation of the JAK/STAT Pathway Leads to BRAF Inhibitor Resistance in BRAFV600E Positive Thyroid Carcinoma

Inducible expression of interleukin-12 augments the efficacy of affinity-tuned chimeric antigen receptors in murine solid tumor models

Chimeric Antigen Receptor T Cell Therapy Targeting Epithelial Cell Adhesion Molecule in Gastric Cancer: Mechanisms of Tumor Resistance

Metastatic pancreatic neuroendocrine tumors feature elevated T cell infiltration.

Sex-Based Clinicopathologic and Survival Differences Among Patients with Pancreatic Neuroendocrine Tumors.

Exposure to Polybrominated Diphenyl Ether Flame Retardants Causes Deoxyribonucleic Acid Damage in Human Thyroid Cells In Vitro

Bispecific CAR T Cells against EpCAM and Inducible ICAM-1 Overcome Antigen Heterogeneity and Generate Superior Antitumor Responses

CSPG4 Is a Potential Therapeutic Target in Anaplastic Thyroid Cancer.

PD1 Blockade Enhances ICAM1-Directed CAR T Therapeutic Efficacy in Advanced Thyroid Cancer.

PD1 blockade enhances ICAM1-directed CAR T therapeutic efficacy in advanced thyroid cancer

Collaborators (4)

Juan Gonzalez-Valdivieso

David Kim

Raymond Hall Yip Louie

Timothy Ullmann

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