Irene Ong

Assistant Professor

University of Wisconsin-Madison

United States

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Dr. Irene Ong is an Assistant Professor at the University of Wisconsin Madison, USA. Her research areas include immunotherapy and radiation therapy applications in cancer treatment, with a particular focus on neuroblastoma and melanoma. She has contributed to recent studies on the efficacy of GD2-directed therapies, immunocytokines, and the role of immune factors in maternal milk. Dr. Ong is also involved in developing next-generation sequencing protocols and exploring gene expression related to respiratory illnesses in farm animals.

Articles (20)

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UNITED STATES

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Paul Harari

Professor and Chairman

University of Wisconsin School of Medicine and Public Health

UNITED STATES

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Min Yu

UNITED STATES

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Ann Palmenberg

Professor

University of Wisconsin-Madison

UNITED STATES

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Irene Ong

Research Interests

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Articles (20)

Low Dose Radiation by Radiopharmaceutical Therapy Enhances GD2 TRAC-CAR T Cells Efficacy in Localized Neuroblastoma.

Large-scale bioreactor production of extracellular vesicles from mesenchymal stromal cells for treatment of acute radiation syndrome

From Bench to Bedside: A Team's Approach to Multidisciplinary Strategies to Combat Therapeutic Resistance in Head and Neck Squamous Cell Carcinoma.

Intratumoral radiation dose heterogeneity augments antitumor immunity in mice and primes responses to checkpoint blockade.

MerTK Drives Proliferation and Metastatic Potential in Triple-Negative Breast Cancer

Administration of intratumoral GD2-directed interleukin-2 immunocytokine and local radiation therapy to activate immune rejection of spontaneous canine melanoma

Assessing immune factors in maternal milk and paired infant plasma antibody binding to human rhinoviruses

Development of a next-generation sequencing protocol for the canine T cell receptor beta chain repertoire

Farm animal exposure, respiratory illnesses, and nasal cell gene expression

Comparative Study of the Effect of Radiation Delivered by Lutetium-177 or Actinium-225 on Anti-GD2 Chimeric Antigen Receptor T Cell Viability and Functions

BAF155 methylation drives metastasis by hijacking super-enhancers and subverting anti-tumor immunity.

Multiomic analysis reveals decidual-specific transcriptional programing of MAIT cells.

PKM2-TMEM33 axis regulates lipid homeostasis in cancer cells by controlling SCAP stability.

Mediator complex subunit 12 is a gatekeeper of SARS-CoV-2 infection in breast cancer cells.

Risk of Late-Onset Breast Cancer in Genetically Predisposed Women.

The landscape of antibody binding in SARS-CoV-2 infection.

Risk of Breast Cancer Among Carriers of Pathogenic Variants in Breast Cancer Predisposition Genes Varies by Polygenic Risk Score.

A lineage-specific requirement for YY1 Polycomb Group protein function in early T cell development.

MixTwice: large-scale hypothesis testing for peptide arrays by variance mixing.

SOX17 integrates HOXA and arterial programs in hemogenic endothelium to drive definitive lympho-myeloid hematopoiesis.

Collaborators (12)

Aussie Suzuki

Peter Halfmann

Krishanu Saha

Bryan P. Bednarz

Reinier Hernandez

Christian Capitini

Randall Kimple

Aleksandar Stanic-Kostic

Deric L. Wheeler

Paul Harari

Min Yu

Ann Palmenberg

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