Irmgard Tegeder

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PI/Professor Dr. med.

Germany

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About

Professor Dr. med. Irmgard Tegeder is a Principal Investigator at Goethe-Universität Frankfurt am Main, Medical Faculty, Germany. Her research focuses on lipidomics, neuroprotection, and inflammatory response, as evidenced by her recent articles on plasma lipidomic profiles in glioma patients, the neuroprotective effects of progranulin, and the roles of lysophosphatidic acid receptors in pain response. Additionally, she investigates the effects of various treatments on neuronal health post-injury and the interplay between feeding behavior and lipid signaling.

Recent Grants

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Progranulin in the Adaptive Response of the Nociceptive System to Damage (A09)

Open Date: 2013-01-01

Close Date: 2016-12-31

Grant: Close

Endocannabinoid deficiency and Parkinson-associated pain (A03)

Open Date: 2013-01-01

Close Date:

Grant: Close

EGFL7 and progranulin (PRGN) in neurogenesis: a notch above as a duo in neural homeostasis. (A03)

Open Date: 2013-01-01

Close Date:

Grant: Close

Nucleoredoxin as regulator of neuronal activity and plasticity (A12)

Open Date: 2009-01-01

Close Date:

Grant: Close

Integrated Research Training Group (MGK)

Open Date: 2009-01-01

Close Date:

Articles (15)

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2025

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2024

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2024

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2024

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2021

Collaborators (3)

Krishnaraj Rajalingam

University Medical Center of the Johannes Gutenberg University Mainz

GERMANY

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Sarah Kittel-Schneider

University Hospital Frankfurt

GERMANY

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Michael K.E. Schäfer

Johannes Gutenberg Universität Universitätsmedizin

GERMANY

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Irmgard Tegeder

Research Interests

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About

Recent Grants

Articles (15)

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Valproic Acid Treatment after Traumatic Brain Injury in Mice Alleviates Neuronal Death and Inflammation in Association with Increased Plasma Lysophosphatidylcholines

Lysophosphatidic Acid Receptors LPAR5 and LPAR2 Inversely Control Hydroxychloroquine-Evoked Itch and Scratching in Mice

Healthy plasma lipidomic signatures depend on sex, age, body mass index, and contraceptives but not perceived stress

Selective neuronal expression of progranulin is sufficient to provide neuroprotective and anti-inflammatory effects after traumatic brain injury

Phosphatidylethanolamine Deficiency and Triglyceride Overload in Perilesional Cortex Contribute to Non-Goal-Directed Hyperactivity after Traumatic Brain Injury in Mice

Cold avoidance and heat pain hypersensitivity in neuronal nucleoredoxin knockout mice

Non-Reproducibility of Oral Rotenone as a Model for Parkinson’s Disease in Mice

AgRP neurons control feeding behaviour at cortical synapses via peripherally derived lysophospholipids

ARAF suppresses ERBB3 expression and metastasis in a subset of lung cancers

Single intracerebroventricular progranulin injection adversely affects the blood–brain barrier in experimental traumatic brain injury

Increased Fat Taste Preference in Progranulin-Deficient Mice

Sphingolipid and Endocannabinoid Profiles in Adult Attention Deficit Hyperactivity Disorder

Reduced exploratory behavior in neuronal nucleoredoxin knockout mice

Failure of Diphtheria Toxin Model to Induce Parkinson-Like Behavior in Mice

Collaborators (3)

Krishnaraj Rajalingam

Sarah Kittel-Schneider

Michael K.E. Schäfer

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