Isabel Merida

Professor

Consejo Superior de Investigaciones Cientificas

Spain

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About

Isabel Merida is a Professor at the Consejo Superior de Investigaciones Científicas in Spain. Her research focuses on immunology, particularly in the mechanisms of T-cell activation and the role of PDZ proteins in viral interactions, including those with SARS-CoV-2. Recent publications highlight her work on diacylglycerol kinases and their implications for immunotherapy and T-lymphocyte function.

Articles (8)

Year:

2024

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2024

Year:

2024

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2023

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2021

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2021

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2020

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2020

Collaborators (3)

Yolanda R. Carrasco

Group Leader/Assistant Professor

SPAIN

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Julien Husson

Professor

Ecole Polytechnique

FRANCE

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Jose M Casasnovas

Professor

Centro Nacional de Biotecnología

SPAIN

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Isabel Merida

Research Interests

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Articles (8)

Modeling of host PDZ-dependent interactions with SARS-CoV-2 envelope protein and changes in PDZ protein expression in macrophages and dendritic cells

Sorting nexin 27–dependent regulation of Lck and CD4 tunes the initial stages of T-cell activation

Diacylglycerol kinases: A look into the future of immunotherapy

Identification of Host PDZ-Based Interactions with the SARS-CoV-2 E Protein in Human Monocytes

Diacylglycerol kinase α inhibition cooperates with PD-1-targeted therapies to restore the T cell activation program

SARS-CoV-2 Spike Protein and Its Receptor Binding Domain Promote a Proinflammatory Activation Profile on Human Dendritic Cells

Diacylglycerol kinase ζ limits IL-2-dependent control of PD-1 expression in tumor-infiltrating T lymphocytes

Diacylglycerol kinase ζ promotes actin cytoskeleton remodeling and mechanical forces at the B cell immune synapse

Collaborators (3)

Yolanda R. Carrasco

Julien Husson

Jose M Casasnovas

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