Isabelle Martin-verstraete

Professor

Université Paris Cité

France

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Isabelle Martin-Verstraete is a Professor at Université Paris Cité in France. Her research focuses on Clostridioides difficile, particularly its mechanisms of antibiotic resistance, phosphoproteomics, and metabolic adaptations. She has also explored the dynamics of gut commensals and their responses to oxidative stress. Her recent publications contribute significantly to understanding bacterial behavior and interactions within the human microbiome.

Articles (10)

Commensal bacteria in the genus Faecalibacterium have been proposed for use as next-generation probiotics, but efforts to cultivate and exploit the potential of these strains have been limited by their sensitivity to O 2 . More broadly, little is known about how commensal and health-associated bacterial species in the human microbiome respond to the oxidative stress that occurs as a result of inflammation in the colon.

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2023

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2021

Collaborators (16)

Lilliana Radoshevich

Assistant Professor

National Jewish Health

UNITED STATES

Isabelle Martin-verstraete

Research Interests

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Articles (10)

The Tolerance of Gut Commensal <i>Faecalibacterium</i> to Oxidative Stress Is Strain Dependent and Relies on Detoxifying Enzymes

The absence of surface D-alanylation, localized on lipoteichoic acid, impacts the Clostridioides difficile way of life and antibiotic resistance

Oxygen response and tolerance mechanisms in Clostridioides difficile

In-Depth Characterization of the Clostridioides difficile Phosphoproteome to Identify Ser/Thr Kinase Substrates

Bacteroides thetaiotaomicron uses a widespread extracellular DNase to promote bile-dependent biofilm formation

Metabolic adaption to extracellular pyruvate triggers biofilm formation in Clostridioides difficile

Responses of Clostridia to oxygen: from detoxification to adaptive strategies

Identification of RNAs bound by Hfq reveals widespread RNA partners and a sporulation regulator in the human pathogen Clostridioides difficile

Listeriolysin S: A bacteriocin from Listeria monocytogenes that induces membrane permeabilization in a contact-dependent manner

Ser/Thr Kinase-Dependent Phosphorylation of the Peptidoglycan Hydrolase CwlA Controls Its Export and Modulates Cell Division in Clostridioides difficile

Collaborators (16)

Lilliana Radoshevich

Eliane Hajnsdorf

Romain Briandet

Johann Peltier

Yannick Tremblay

Jazmin Meza-Torres

Filipe Folgosa

Helene Bierne

Sandrine Auger

Claire Morvan

Pierre BOUDRY

Maxence Lejars

Wiep Klaas Smits

Olga Soutourina

Thierry Lequeux

Anne-Aurélie Lopes

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