Issay Kitabayashi

Chief

National Cancer Center Research Institute

Japan

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About

Issay Kitabayashi is the Chief at the National Cancer Center Research Institute in Japan. His research focuses on cancer biology, particularly the mechanisms underlying breast cancer carcinogenesis, the role of IDH mutations in chondrosarcoma, and the influence of autophagy on tumor suppressor enzymes. Recent publications highlight his work on hematologic malignancies and the effects of specific genetic mutations on cancer progression.

Articles (7)

Year:

2021

Year:

2021

Year:

2021

Year:

2021

Year:

2021

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2020

Year:

2020

Collaborators (3)

Keiichi Tamai

Head

JAPAN

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Makoto Nakagawa

Duke University

UNITED STATES

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Shusaku Shibutani

Associate Professor

Yamaguchi University

JAPAN

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Issay Kitabayashi

Research Interests

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Articles (7)

Prognostic impact of IDH mutations in chondrosarcoma

Ppp6c deficiency accelerates K-ras<sup>G12D</sup>-induced tongue carcinogenesis

The membrane-linked adaptor FRS2β fashions a cytokine-rich inflammatory microenvironment that promotes breast cancer carcinogenesis.

Tip60 activates Hoxa9 and Meis1 expression through acetylation of H2A.Z, promoting MLL-AF10 and MLL-ENL acute myeloid leukemia.

CDKN1C-mediated growth inhibition by an EZH1/2 dual inhibitor overcomes resistance of mantle cell lymphoma to ibrutinib.

Autophagy regulates levels of tumor suppressor enzyme protein phosphatase 6.

Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia.

Collaborators (3)

Keiichi Tamai

Makoto Nakagawa

Shusaku Shibutani

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