Ivan Vokřál

Has grant

Assistant Professor

Charles University, Faculty of Pharmacy in Hradec Kralove

Czech Republic

Research Interests

Contact this professor

Get a free first email built on one of their papers, ready for you to edit and send yourself.

About

Ivan Vokřál is an Assistant Professor at Charles University, Faculty of Pharmacy in Hradec Kralove, Czech Republic. His research interests include the biotransformation of anthelmintics, their environmental impact, and drug resistance in nematodes. He has recently published articles focusing on the effects of anthelmintics on non-target organisms and the evaluation of antiviral drugs and their mechanisms, particularly in relation to P-glycoprotein mediated efflux. His work contributes significantly to understanding drug efficacy in both veterinary and human medicine.

Recent Grants

Grant: Close

In vitro and ex vivo models to study drug-drug interactions of antiviral drugs on intestinal transporters

Open Date: 2018-01-01

Close Date: 2020-12-31

Articles (13)

Year:

2025

Year:

2023

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Year:

2021

Year:

2021

Year:

2020

Collaborators (6)

Thomas Kurz

Heinrich Heine University Düsseldorf

GERMANY

View details

Lukáš Červený

Associate Professor

Univerzita Karlova Farmaceutická Fakulta v Hradci Králové

CZECH REPUBLIC

View details

Hana Vlčková

lecturer and research analytical chemist

Charles University, Faculty of Pharmacy in Hradec Kralove

CZECH REPUBLIC

View details

Rona Karahoda

Assistant Professor

Charles University

CZECH REPUBLIC

View details

Ondřej Holas

Charles University

CZECH REPUBLIC

View details

Ondrej Martinec

Assistant Professor

Charles University, Faculty of Medicine in Pilsen

CZECH REPUBLIC

View details

ApplyKite TwinLearns as you apply

Make your next move.

Prepare your application

Review drafts before you send them.

Ivan Vokřál

Research Interests

Contact this professor

About

Recent Grants

Articles (13)

Biotransformation of anthelmintics in nematodes in relation to drug resistance

Anthelmintics in the environment: Their occurrence, fate, and toxicity to non-target organisms

Albendazole from ovine excrements in soil and plants under real agricultural conditions: Distribution, persistence, and effects

Effect of P-glycoprotein and Cotreatment with Sofosbuvir on the Intestinal Permeation of Tenofovir Disoproxil Fumarate and Tenofovir Alafenamide Fumarate

Assessing the Anthelmintic Candidates BLK127 and HBK4 for Their Efficacy on Haemonchus contortus Adults and Eggs, and Their Hepatotoxicity and Biotransformation

Evaluation of the Potency of Anti-HIV and Anti-HCV Drugs to Inhibit P-Glycoprotein Mediated Efflux of Digoxin in Caco-2 Cell Line and Human Precision-Cut Intestinal Slices

Precision-cut rat placental slices as a model to study sex-dependent inflammatory response to LPS and Poly I:C

Environmental circulation of the anthelmintic drug albendazole affects expression and activity of resistance-related genes in the parasitic nematode Haemonchus contortus

Determination of Antiviral Drugs and Their Metabolites Using Micro-Solid Phase Extraction and UHPLC-MS/MS in Reversed-Phase and Hydrophilic Interaction Chromatography Modes

Proof of the environmental circulation of veterinary drug albendazole in real farm conditions

Rifampicin Induces Gene, Protein, and Activity of P-Glycoprotein (ABCB1) in Human Precision-Cut Intestinal Slices

Use of Precision-Cut Tissue Slices as a Translational Model to Study Host-Pathogen Interaction

Sub-lethal doses of albendazole induce drug metabolizing enzymes and increase albendazole deactivation in Haemonchus contortus adults

Collaborators (6)

Thomas Kurz

Lukáš Červený

Hana Vlčková

Rona Karahoda

Ondřej Holas

Ondrej Martinec

Make your next move.