Iwona Gabriel

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PhD, D.Sc, Assoc. Prof.

Gdańsk University of Technology, Faculty of Chemistry

Poland

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About

Dr. Iwona Gabriel is an Associate Professor at Gdańsk University of Technology in the Chemical Faculty, Poland. Her research primarily focuses on antifungal chemotherapy, exploring the interactions of various compounds with yeast topoisomerase II, and the synthesis of bioactive derivatives. Recent publications highlight her work on L-Methionine biosynthesis enzymes and novel methods for endotoxins removal from chitosan hydrogel.

Recent Grants

Grant: Close

Enzymes of the L-methionine biosynthetic pathway as novel molecular targets for antifungal chemotherapy

Open Date: 2021-07-01

Close Date: 2025-07-01

Grant: Close

Aromatic aminotransferases from Candida albicans as molecular targets for antifungal chemotherapy.

Open Date: 2016-02-01

Close Date: 2019-02-01

Grant: Close

The unique fungal lysine biosynthesis enzymes new targets for antifungal agents?

Open Date: 2011-05-01

Close Date: 2014-07-01

Articles (11)

Year:

2024

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2024

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2023

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2022

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2022

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2022

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2021

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2021

Year:

2021

Year:

2021

Year:

2020

Collaborators (13)

Ioannis Kostakis

Associate Professor

GREECE

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Szymon Mania

Research and teaching assistant

University of Gdańsk

POLAND

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Kamila Rząd

assistant profesor

Politechnika Gdanska

POLAND

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Robert Tylingo

University of Gdańsk

POLAND

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University of Gdańsk

POLAND

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Damian Neubauer

Medical University of Gdansk

POLAND

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Piotr Szweda

University of Gdańsk

POLAND

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Iwona Gabriel

Research Interests

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About

Recent Grants

Articles (11)

Targeting yeast topoisomerase II by imidazo and triazoloacridinone derivatives resulting in their antifungal activity

Fungal L-Methionine Biosynthesis Pathway Enzymes and Their Applications in Various Scientific and Commercial Fields

Xanthone synthetic derivatives with high anticandidal activity and positive mycostatic selectivity index values

Antifungal Effect of Penicillamine Due to the Selective Targeting of L-Homoserine O-Acetyltransferase

A Novel Method of Endotoxins Removal from Chitosan Hydrogel as a Potential Bioink Component Obtained by CO2 Saturation

Targeting DNA Topoisomerase II in Antifungal Chemotherapy

Quest for the Molecular Basis of Improved Selective Toxicity of <i>All-Trans</i> Isomers of Aromatic Heptaene Macrolide Antifungal Antibiotics

The Effect of Conjugation with Octaarginine, a Cell-Penetrating Peptide on Antifungal Activity of Imidazoacridinone Derivative

Antifungal Activity of Capridine β as a Consequence of Its Biotransformation into Metabolite Affecting Yeast Topoisomerase II Activity

A new 1-nitro-9-aminoacridine derivative targeting yeast topoisomerase II able to overcome fluconazole-resistance.

‘Acridines’ as New Horizons in Antifungal Treatment

Collaborators (13)

Ioannis Kostakis

Szymon Mania

Kamila Rząd

Robert Tylingo

Marek Wojciechowski

Slawomir Milewski

Joanna Pilch

Tomasz Laskowski

Paweł Szczeblewski

Julia Borzyszkowska-Bukowska

Ewa Augustin

Damian Neubauer

Piotr Szweda

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