J. David Spence

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Professor

University of Western Ontario

Canada

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About

J. David Spence is a Professor at the University of Western Ontario in Canada. His research focuses on vascular health and cardiovascular risk reduction, with recent articles on blood flow in the cerebral cortex, vessel wall volume measurement in carotid arteries, and the effects of probiotics on atherosclerosis. He has also explored the cost-utility analysis of treatments for patients with prediabetes and a history of stroke.

Recent Grants

Grant: Close

Intestinal microbiome and atherosclerosis

Open Date: 2014-01-01

Close Date: 2016-01-01

Grant: Close

Aldosterone antagonism and atherosclerosis

Open Date: 2011-01-01

Close Date: 2013-01-01

Grant: Close

Canadian Atherosclerosis Imaging Network

Open Date: 2008-01-01

Close Date: 2015-01-01

Grant: Close

Various projects

Open Date: 1977-01-01

Close Date: 2010-01-01

Articles (20)

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2022

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2022

Collaborators (2)

Aaron Fenster

Western University

CANADA

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Garret A. FitzGerald

University of Pennsylvania

UNITED STATES

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J. David Spence

Research Interests

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Contact this professor

About

Recent Grants

Articles (20)

Blood flow in the human cerebral cortex: Large-scale pial vascularization and 1D simulation

Letter to the Editor From Spence: [Prevalence and Characteristics of Low-Renin Hypertension in a Primary Care Population]

Correspondence on: “Subclinical atherosclerosis: More data – More insights into prevention”

Homocysteine and Myocardial Injury

Reducing Cardiovascular Risk: The Potential of Plant-Based Meat Alternatives and Egg Substitutes

Poor Results with “Best Medical Therapy” in Patients with Asymptomatic Carotid Stenosis

Vessel Wall Volume and Plaque Volume Should Replace Carotid Intima–Media Thickness

Prior-knowledge Embedded U-Net based Fully Automatic Vessel Wall Volume Measurement of the Carotid Artery in 3D Ultrasound Image

Potential effects of probiotics on atherosclerosis

Cost‐Utility Analysis of Low‐Dose Pioglitazone in a Population With Prediabetes and a History of Stroke or Transient Ischemic Attack

Vertebrobasilar ischemia: Some less recognized aspects

B vitamins for NASH: Use methylcobalamin, not cyanocobalamin

Cardiovascular effects of TMAO and other toxic metabolites of the intestinal microbiome

Carotid Plaque Burden Is a Stronger Predictor of Cardiovascular Risk Than IMT

Cerebrovascular Disease, Cardiovascular Disease, and Chronic Kidney Disease: Interplays and Influences

Homocysteine and Thrombophilia in Pulmonary Hypertension

Identifying High-Risk Nonstenotic Carotid Artery Disease

Acetaminophen, Nonsteroidal Anti-Inflammatory Drugs, and Hypertension

In Memoriam: Jim Toole, MD: Ahead of His Time

Problem in the Recent American Heart Association Guideline on Secondary Stroke Prevention: B Vitamins to Lower Homocysteine Do Prevent Stroke

Collaborators (2)

Aaron Fenster

Garret A. FitzGerald

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