Ja Hyun Koo

Assistant Professor

Seoul National University

South Korea

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About

Ja Hyun Koo is an Assistant Professor at Seoul National University in South Korea. His research focuses on metabolic disorders and liver diseases, particularly the mechanisms underlying hepatic fatty acid oxidation, and the roles of various proteins and signaling pathways in liver injury and cell survival. Recent publications include studies on YAP/TAZ interactions with liver disease progression and the protective effects of NRF2 in hepatocytes.

Articles (12)

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2025

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2024

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2024

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2024

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2023

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2023

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2023

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2022

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2022

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2021

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2021

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2020

Collaborators (6)

Sang Geon Kim

Professor

Dongguk University

SOUTH KOREA

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Hyun-Jeong Ko

Professor

Changwon National University

SOUTH KOREA

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Bruce A. Vallance

CANADA

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Kim Jiyoon

Associate Professor

Catholic University of Korea School of Medicine

SOUTH KOREA

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Di Yang

University of Texas Southwestern Medical Center

UNITED STATES

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Wondong Kim

Associate Professor

Hanyang University - ERICA Campus

SOUTH KOREA

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Ja Hyun Koo

Research Interests

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About

Articles (12)

Stabilizing hepatic fatty acid oxidation: Editorial on “USP29 alleviates the progression of MASLD by stabilizing ACSL5 through K48 deubiquitination”

Interplay between YAP/TAZ and metabolic dysfunction-associated steatotic liver disease progression

Hepatocyte GPCR signaling regulates IRF3 to control hepatic stellate cell transdifferentiation

Mitochondrial stress activates YAP/TAZ through RhoA oxidation to promote liver injury

ERdj5 protects goblet cells from endoplasmic reticulum stress-mediated apoptosis under inflammatory conditions.

Identification of Small GTPases That Phosphorylate IRF3 through TBK1 Activation Using an Active Mutant Library Screen.

Identification of the primary ciliary proteins IFT38 and IFT144 to enhance serum-mediated YAP activation and cell proliferation

Nuclear factor (erythroid-derived 2)-like 2 counter-regulates thymosin beta-4 expression and primary cilium formation for HeLa cervical cancer cell survival.

NRF2-mediated SIRT3 induction protects hepatocytes from ER stress-induced liver injury.

Ablation of USP21 in skeletal muscle promotes oxidative fibre phenotype, inhibiting obesity and type 2 diabetes

Signaling Nodes Associated with Endoplasmic Reticulum Stress during NAFLD Progression

Induction of AP-1 by YAP/TAZ contributes to cell proliferation and organ growth

Collaborators (6)

Sang Geon Kim

Hyun-Jeong Ko

Bruce A. Vallance

Kim Jiyoon

Di Yang

Wondong Kim

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