Jacob McPhail

Professional Researcher

University of California, San Francisco

United States

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Jacob McPhail is a Professional Researcher at the University of California, San Francisco, USA. His research focuses on microglial interactions with tau proteins, disease-associated protein detection techniques, molecular mechanisms of PI4K regulation, and the structural basis of inhibitor specificity in Plasmodium falciparum. He is also involved in studying the c10orf76‐PI4KB complex and its role in Golgi PI4P levels and viral replication.

Articles (5)

Year:

2024

Year:

2023

Year:

2023

Year:

2020

Year:

2020

Collaborators (1)

Kiani Jeacock

Teaching Associate

University Of Strathclyde

UNITED KINGDOM

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Jacob McPhail

Research Interests

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Articles (5)

Microglia internalize tau monomers and fibrils using distinct receptors but similar mechanisms

Two-color coincidence single-molecule pulldown for the specific detection of disease-associated protein aggregates

Molecular mechanisms of PI4K regulation and their involvement in viral replication

Structural Basis for Inhibitor Potency and Selectivity of Plasmodium falciparum Phosphatidylinositol 4-Kinase Inhibitors.

Characterization of the c10orf76‐PI4KB complex and its necessity for Golgi PI4P levels and enterovirus replication

Collaborators (1)

Kiani Jeacock

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