Jae-Young Um

Professor

Kyungpook National University

South Korea

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Jae-Young Um is a Professor at Kyung Hee University, South Korea. His research focuses on the mechanisms of muscle atrophy, obesity, and cancer cachexia, with recent articles exploring topics such as mitochondrial dynamics, adipose tissue browning, and the effects of various compounds on cancer cell behavior. His work contributes to understanding metabolic diseases and developing potential therapeutic strategies.

Articles (20)

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2025

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2021

Collaborators (6)

Jinbong Park

SOUTH KOREA

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Jungtae Leem

SOUTH KOREA

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Seok-Geun Lee

Professor

Kyungpook National University

SOUTH KOREA

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Junhee Lee

Professor

Kyungpook National University

SOUTH KOREA

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Kwang Seok Ahn

Kyungpook National University

SOUTH KOREA

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Woo Yong Park

Vanderbilt University School of Medicine

UNITED STATES

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Jae-Young Um

Research Interests

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Articles (20)

Regulating Sirtuin 3-mediated mitochondrial dynamics through vanillic acid improves muscle atrophy in cancer-induced cachexia.

Browning of inguinal white adipose tissue by the novel lignan (-)-secoisolariciresinol 4-O-methyl ether attenuates diet-induced obesity through mitochondrial and peroxisomal activation.

4-hydroxybenzoic acid induces browning of white adipose tissue through the AMPK-DRP1 pathway in HFD-induced obese mice

FXR-ApoC2 pathway activates UCP1-mediated thermogenesis by promoting the browning of white adipose tissues

The combination of water extracts of Curcumae Radix and Syzygii Flos improves benign prostatic hyperplasia by suppressing testosterone-induced proliferation of prostate cells in vivo and in vitro

Epigallocatechin gallate protects against fat and muscle atrophy in B16BL6 melanoma-bearing mice on a high-fat diet

Activation of autophagy, paraptosis, and ferroptosis by micheliolide through modulation of the MAPK signaling pathway in pancreatic and colon tumor cells

Brassinin alleviates cancer cachexia by suppressing diverse inflammatory mechanisms in mice

Chrysanthemum indicum L. ameliorates muscle atrophy by improving glucose tolerance in CT26-induced cancer cachexia

Fangchinoline targets human renal cell carcinoma cells through modulation of apoptotic and non‑apoptotic cell deaths

Euphorbiasteroid Induces Apoptosis as Well as Autophagy through Modulating SHP-1/STAT3 Pathway in Hepatocellular Carcinoma Cells

Brassinin Induces Apoptosis, Autophagy, and Paraptosis via MAPK Signaling Pathway Activation in Chronic Myelogenous Leukemia Cells

Anmyungambi Decoction Ameliorates Obesity through Activation of Non-Shivering Thermogenesis in Brown and White Adipose Tissues

Ellagic acid improves benign prostate hyperplasia by regulating androgen signaling and STAT3.

Potential Application of Leelamine as a Novel Regulator of Chemokine-Induced Epithelial-to-Mesenchymal Transition in Breast Cancer Cells

Leelamine Modulates STAT5 Pathway Causing Both Autophagy and Apoptosis in Chronic Myelogenous Leukemia Cells

Raphani Semen (<i>Raphanus sativus</i> L.) Ameliorates Alcoholic Fatty Liver Disease by Regulating De Novo Lipogenesis

Fruit of Gardenia jasminoides Induces Mitochondrial Activation and Non-Shivering Thermogenesis through Regulation of PPARγ

Pyrimethamine Modulates Interplay between Apoptosis and Autophagy in Chronic Myelogenous Leukemia Cells

LDL cholesterol promotes the proliferation of prostate and pancreatic cancer cells by activating the STAT3 pathway

Collaborators (6)

Jinbong Park

Jungtae Leem

Seok-Geun Lee

Junhee Lee

Kwang Seok Ahn

Woo Yong Park

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