Jaehee Lee

Vertex Pharmaceuticals

United States

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Articles (9)

Year:

2025

Year:

2024

Year:

2024

Year:

2023

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Collaborators (6)

Marisa C. Kozlowski

University of Pennsylvania

UNITED STATES

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Binh Khanh Mai

University of Pittsburgh

UNITED STATES

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Bo Qu

Boehringer Ingelheim Pharmaceuticals Inc

UNITED STATES

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Filippo Romiti

Assistant Professor

University of Texas at Dallas

UNITED STATES

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Ming Joo Koh

President's Assistant Professor

National University of Singapore (NUS)

SINGAPORE

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Joyce Leung

Boehringer Ingelheim Pharmaceuticals Inc

UNITED STATES

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Jaehee Lee

Research Interests

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Articles (9)

Synthesis and Functionalization of Aziridines: A Perspective View from Pharmaceutical Industries

A Chiral Pool Strategy for the Synthesis of a SMARCA2 Degrading PROTAC

Development of a Scalable Synthesis toward a KRAS G12C Inhibitor Building Block Bearing an All-Carbon Quaternary Stereocenter, Part 1: From Discovery Route to Kilogram-Scale Production

Mechanistic Insights of Copper Catalyzed Trifluoromethyl Aziridine Opening: Regioselective and Stereospecific Aryl Grignard Addition

Building a Quaternary Stereogenic Center on Dihydroazaindole Carboxylic Acid through Scalable Process Development

Recent Advances in Non-Precious Metal Catalysis

Diastereo- and enantioselective synthesis of compounds with a trifluoromethyl- and fluoro-substituted carbon centre

Scalable Process of Spiro(cyclopropane)oxazepane Pyridine Carboxylic Acid through Kulinkovich, Mitsunobu, and Pd-Catalyzed Intramolecular C–N Coupling

Copper Catalyzed Regioselective and Stereospecific Aziridine Opening with Pyridyl Grignard Nucleophiles

Collaborators (6)

Marisa C. Kozlowski

Binh Khanh Mai

Bo Qu

Filippo Romiti

Ming Joo Koh

Joyce Leung

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