Jaime Rubio-Martinez

Full Professor

University of Barcelona

Spain

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Jaime Rubio-Martinez is a Full Professor at the University of Barcelona, Spain. His research focuses on neuroprotection in Parkinson's disease, the molecular interactions of SARS-CoV-2, and the development of inhibitors targeting various proteins implicated in disease pathology. His recent work includes studies on polyphenols' effects on protein aggregation and the discovery of novel allosteric sites in critical cancer-related proteins.

Articles (16)

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2025

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2023

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2022

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FRANCE

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Ana Jiménez Alesanco

Instituto de Física Interdisciplinar y Sistemas Complejos

SPAIN

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Caroline Mauvezin

Ramon y Cajal Group Leader

University of Barcelona

SPAIN

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Andrés Garzón-Ruiz

University of Castilla-La Mancha

SPAIN

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Sonia Vega Sánchez

Universidad de Zaragoza

SPAIN

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Olga Abian

Universidad de Zaragoza

SPAIN

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Jaime Rubio-Martinez

Research Interests

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About

Articles (16)

Oleuropein Aglycone, an Olive Polyphenol, Influences Alpha-Synuclein Aggregation and Exerts Neuroprotective Effects in Different Parkinson’s Disease Models

Induction of the Inflammasome by the SARS‐CoV‐2 Accessory Protein ORF9b, Abrogated by Small‐Molecule ORF9b Homodimerization Inhibitors

Shedding Light on Dark Chemical Matter: The Discovery of a SARS-CoV-2 Mpro Main Protease Inhibitor through Intensive Virtual Screening and In Vitro Evaluation

The Discovery of inhibitors of the SARS-CoV-2 S protein through computational drug repurposing

Assessment of the bound conformation of bombesin to the BB1 and BB2 receptors

A hotspot for posttranslational modifications on the androgen receptor dimer interface drives pathology and anti-androgen resistance

α4-α5 Helices on Surface of KRAS Can Accommodate Small Compounds That Increase KRAS Signaling While Inducing CRC Cell Death

A Step Forward toward Selective Activation/Inhibition of Bak, a Pro-Apoptotic Member of the Bcl-2 Protein Family: Discovery of New Prospective Allosteric Sites Using Molecular Dynamics

A hotspot for posttranslational modifications on the androgen receptor dimer interface drives pathology and anti-androgen resistance

alpha 4-alpha 5 Helices on Surface of KRAS Can Accommodate Small Compounds That Increase KRAS Signaling While Inducing CRC Cell Death

Autochthonous Peruvian Natural Plants as Potential SARS-CoV-2 Mpro Main Protease Inhibitors

Autochthonous Peruvian Natural Plants as Potential SARS-CoV-2 Mpro Main Protease Inhibitors

Discovery of Hit Compounds Targeting the P4 Allosteric Site of K-RAS, Identified through Ensemble-Based Virtual Screening

Shedding light on the binding mechanism of kinase inhibitors BI-2536, Volasetib and Ro-3280 with their pharmacological target PLK1

Shedding light on the binding mechanism of kinase inhibitors BI-2536 Volasetib and Ro-3280 with their pharmacological target PLK1,

Effects of solvents on the conformational profile of Balaram's peptide: a computational study

Collaborators (10)

Eva Estébanez-Perpiñá

Jose M. Granadino-Roldan

Neus Agell

Adrian Velazquez-Campoy

Muriel Le Romancer

Ana Jiménez Alesanco

Caroline Mauvezin

Andrés Garzón-Ruiz

Sonia Vega Sánchez

Olga Abian

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