James A Bull

Reader in Synthetic Chemistry

Imperial College London

United Kingdom

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James A Bull is a Reader in Synthetic Chemistry at Imperial College London, UK. His research focuses on the development of novel synthetic methodologies, including the synthesis of cyclic sulfilimines and sulfoximines, as well as electrochemical copper catalysis. Recent articles highlight his work on functionalization reactions and the synthesis of complex molecules, demonstrating significant advancements in synthetic organic chemistry.

Articles (23)

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2025

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2022

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2022

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2022

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2022

Collaborators (5)

Renzo Luisi

ITALY

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Philip Miller

Senior Lecturer

Imperial College London

UNITED KINGDOM

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James Harry Moore

AstraZeneca UK Limited

UNITED KINGDOM

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anne sophie voisin-chiret

Université de Caen Normandie

FRANCE

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Alan Armstrong

Imperial College London

UNITED KINGDOM

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James A Bull

Research Interests

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About

Articles (23)

Synthesis of Cyclic Sulfilimines and Sulfoximines via Copper‐Mediated C(sp2)–H Sulfanylation of Benzylamines with a Catalytic Transient Directing Group

Electrochemical Copper Catalysis: A Triple Catalytic System for Transient C(sp2)–H Functionalization through Mediated Electrolysis

Synthesis of gem-Difluorocyclobutanes: Organolanthanum Enabled Synthesis and Divergent Catalytic Functionalization of gem-Difluorocyclobutanols

Catalytic SuFEx Reactivity of Sulfonimidoyl Fluorides with Functionalized Amines with Automation Applicable Conditions

Bidentate NHC‐Containing Ligands for Copper Catalysed Synthesis of Functionalised Diaryl Ethers

Unconventional reactivity of sulfonyl fluorides

When is an Imine Directing Group a Transient Imine Directing Group in C−H Functionalization?

Enantioselective Phase-Transfer-Catalyzed Synthesis of Spirocyclic Azetidine Oxindoles

Synthesis of Pyrazolesulfoximines Using α-Diazosulfoximines with Alkynes

Sulfur stereochemistry takes centre stage

Synthesis of 3,3-Disubstituted Thietane Dioxides

A Continuous Flow Process for the Defluorosilylation of HFC-23 and HFO-1234yf

Synthesis of oxetane and azetidine ethers as ester isosteres by Brønsted acid catalysed alkylation of alcohols with 3-aryl-oxetanols and 3-aryl-azetidinols

Dual Copper- and Aldehyde-Catalyzed Transient C–H Sulfonylation of Benzylamines

On the Mechanism and Selectivity of Palladium-Catalyzed C(sp3)–H Arylation of Pyrrolidines and Piperidines at Unactivated C4 Positions: Discovery of an Improved Dimethylaminoquinoline Amide Directing Group

Synthesis of aza-S(VI) motifs

4-Membered Ring Carbocations: A Positive Development in the Synthesis of 3,3-Disubstituted Oxetanes and Azetidines

Synthesis of Sulfoximines and Sulfonimidamides Using Hypervalent Iodine Mediated NH Transfer

Oxetanes in Drug Discovery Campaigns

Synthesis of Sulfoximine Propargyl Carbamates under Improved Conditions for Rhodium Catalyzed Carbamate Transfer to Sulfoxides

Amine‐Catalyzed Copper‐Mediated C−H Sulfonylation of Benzaldehydes via a Transient Imine Directing Group**

Stereoselective Palladium‐Catalyzed C(sp3)−H Mono‐Arylation of Piperidines and Tetrahydropyrans with a C(4) Directing Group

Oxetan-3-ols as 1,2-bis-Electrophiles in a Brønsted-Acid-Catalyzed Synthesis of 1,4-Dioxanes

Collaborators (5)

Renzo Luisi

Philip Miller

James Harry Moore

anne sophie voisin-chiret

Alan Armstrong

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