James Birchler

Associate Professor/Professor/Curators' Professor

University of Missouri Columbia

United States

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James Birchler is an Associate Professor at the University of Missouri Columbia, USA. His research focuses on genomic balance effects on gene expression, aneuploidy, and the behavior of long non-coding RNAs in maize. He has contributed significantly to the understanding of ploidy variation and genetic elements in plant systems, as reflected in his recent publications.

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2025

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2022

Collaborators (3)

Hua Yang

University of Missouri

UNITED STATES

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Jianming Yu

Professor, Pioneer Distinguished Chair in Maize Breeding

Iowa State University

UNITED STATES

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Thomas Juenger

Professor

University of Texas at Austin

UNITED STATES

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James Birchler

Research Interests

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About

Articles (19)

Genomic balance effects on gene expression and the organism

Genome imbalance modulates the expression of long non‐coding RNAs in maize

Aneuploidy and ploidy variation conditioned by the B chromosome of maize

Review of Lee Kass's “From Chromosomes to Mobile Genetic Elements: The Life and Work of Nobel Laureate Barbara McClintock”

When is it subfunctionalization and when is it not?

Inverse and Proportional Trans Modulation of Gene Expression in Human Aneuploidies

Synthetic minichromosomes in plants: past, present, and promise

Genomic imbalance modulates transposable element expression in maize

Highlighting plant science with a GENETICS and G3 series on Plant Genetics and Genomics

Highlighting plant science with a GENETICS and G3 series on Plant Genetics and Genomics

MicroRNAs play regulatory roles in genomic balance

Non–B-form DNA tends to form in centromeric regions and has undergone changes in polyploid oat subgenomes

Transgenic direct terminal repeats of Dissociation (Ds) produce chromosomal breakage in maize

Variation for maize B chromosome preferential fertilization: a component of the B chromosome drive mechanism

Centromeres: From chromosome biology to biotechnology applications and synthetic genomes in plants

Focus on plant genetics: Celebrating Gregor Mendel’s 200th birth anniversary

The multiple fates of gene duplications: Deletion, hypofunctionalization, subfunctionalization, neofunctionalization, dosage balance constraints, and neutral variation

Dosage-sensitive miRNAs trigger modulation of gene expression during genomic imbalance in maize

Effect of aneuploidy of a non‐essential chromosome on gene expression in maize

Collaborators (3)

Hua Yang

Jianming Yu

Thomas Juenger

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