James Cai

Professor

Texas A&M University

United States

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Professor James Cai is a faculty member at Texas A&M University in the United States. His research areas include single-cell RNA sequencing, gene regulation, and epigenetic variability, as evidenced by his recent articles on topics such as co-embedding of peaks and genes, gene function, and cellular communication. His work contributes significantly to understanding tumor heterogeneity and gene regulatory networks.

Articles (17)

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2025

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2025

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2025

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2025

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2025

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2025

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2024

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2023

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2022

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2022

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2022

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2022

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2022

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2022

Collaborators (4)

Stephen Safe

Texas A&M University

UNITED STATES

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Robert S Chapkin

Distinguished Professor

Texas A&M University

UNITED STATES

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Amanda Mahnke

Visiting Assistant Professor, ACES Faculty Fellow

Texas A&M University Health Sciences Center

UNITED STATES

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Rajesh C. Miranda

UNITED STATES

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James Cai

Research Interests

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Articles (17)

scPOEM: robust co-embedding of peaks and genes revealing peak–gene regulation

Functional diversification of the MADS-box gene family in fine-tuning the dimorphic transition of Talaromyces marneffei

Expression of Prooncogenic Nuclear Receptor 4A (NR4A)-Regulated Genes β1-Integrin and G9a Inhibited by Dual NR4A1/2 Ligands

Exploring cell-to-cell variability and functional insights through differentially variable gene analysis

Single-Cell RNA Sequencing Reveals Extensive Heterogeneity and Unique Gene Trajectories in Non-Transformed and Transformed Human Lung Epithelial Cells: Insights into the Role of LncRNAs in Tumor Heterogeneity

Gene function revealed at the moment of stochastic gene silencing

Controlled noise: evidence of epigenetic regulation of single-cell expression variability

Gene knockout inference with variational graph autoencoder learning single-cell gene regulatory networks

Quantum gene regulatory networks

scTenifoldXct: A semi-supervised method for predicting cell-cell interactions and mapping cellular communication graphs

Aryl Hydrocarbon Receptor (AhR) Signaling in Colonic Cells and Tumors

Ablation of long noncoding RNA MALAT1 activates antioxidant pathway and alleviates sepsis in mice.

Transcriptomic Profiling of Gene Expression Associated with Granulosa Cell Tumor Development in a Mouse Model.

Association of pyroptosis and severeness of COVID-19 as revealed by integrated single-cell transcriptome data analysis.

Gag-like proteins: Novel mediators of prenatal alcohol exposure in neural development.

scInTime: A Computational Method Leveraging Single-Cell Trajectory and Gene Regulatory Networks to Identify Master Regulators of Cellular Differentiation.

The Brief Case: Corynebacterium amycolatum in a Relapsing Urinary Tract Infection of a Feline Patient.

Collaborators (4)

Stephen Safe

Robert S Chapkin

Amanda Mahnke

Rajesh C. Miranda

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