James Iatridis

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Professor

Icahn School of Medicine at Mount Sinai

United States

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About

James Iatridis is a Professor at the Icahn School of Medicine at Mount Sinai in the United States. His research primarily focuses on the mechanisms of disc degeneration, cytokine response in spinal tissues, and skeletal muscle regeneration. His recent articles explore topics such as animal models of disc degeneration, neuroinflammation associated with spinal injuries, and innovative biomaterials for intervertebral disc therapy.

Recent Grants

Grant: Open

Role of TNFalpha in discogenic pain progression and as a treatment target

Open Date: 2022-02-01

Close Date: 2026-12-31

Grant: Open

Mechanisms for Regenerative Healing in Intervertebral Discs

Open Date: 2022-01-15

Close Date: 2026-12-31

Grant: Close

2019 ORS/PSRS 5th International Spine Research Symposium (Orthopaedic Research Society/Philadelphia Spine Research Society)

Open Date: 2019-08-01

Close Date: 2020-07-31

Grant: Close

Diabetes Induced Disc Degeneration and Prevention

Open Date: 2016-06-10

Close Date: 2021-05-31

Grant: Close

Diabetes Induced Disc Degeneration and Prevention

Open Date: 2016-06-10

Close Date: 2021-05-31

Articles (15)

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2025

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2022

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2022

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SWITZERLAND

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Dalin Wang

University of Kansas Medical Center

UNITED STATES

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Christine Le Maitre

Professor of Musculoskeletal Cell Biology and Tissue Regeneration

The University of Sheffield - The Edge

UNITED KINGDOM

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James Iatridis

Research Interests

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About

Recent Grants

Articles (15)

Animal Models of Disc Degeneration Using Puncture Injury: A 20 Year Perspective

TNFα Receptor 1 and Not Receptor 2 Affect Annulus Fibrosus and Nucleus Pulposus Response to Cytokine Challenge in a Rat Model

The role of the complement system in disc degeneration and Modic changes

Myoblast-derived ADAMTS-like 2 promotes skeletal muscle regeneration after injury

Annulus Fibrosus Injury Induces Acute Neuroinflammation and Chronic Glial Response in Dorsal Root Ganglion and Spinal Cord—An In Vivo Rat Discogenic Pain Model

Spinal Cord Sensitization and Spinal Inflammation from an In Vivo Rat Endplate Injury Associated with Painful Intervertebral Disc Degeneration

Teaching Tissue Repair Through an Inquiry-Based Learning Bioadhesives Module

Galectin‐3 and RAGE differentially control advanced glycation endproduct‐induced collagen damage in murine intervertebral disc organ culture

Mechanisms and clinical implications of intervertebral disc calcification.

Ex vivo biomechanical evaluation of Acute lumbar endplate injury and comparison to annulus fibrosus injury in a rat model

Genipin-crosslinked fibrin seeded with oxidized alginate microbeads as a novel composite biomaterial strategy for intervertebral disc cell therapy

Extracellular Vesicles as an Emerging Treatment Option for Intervertebral Disc Degeneration: Therapeutic Potential, Translational Pathways, and Regulatory Considerations

Accelerometry Data Delineate Phases of Recovery and Supplement Patient-Reported Outcome Measures Following Lumbar Laminectomy

A perspective on the ORS Spine Section initiative to develop a multi‐species JOR Spine histopathology series

Single‐cell RNA‐sequencing atlas of bovine caudal intervertebral discs: Discovery of heterogeneous cell populations with distinct roles in homeostasis

Collaborators (8)

Sarah Gullbrand

Woojin Han

Robert Sebra

Jennifer Weiser

Svenja Illien-Junger

Stefan Dudli

Dalin Wang

Christine Le Maitre

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