James O'Connor

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Professor and Team Leader

Institute of Cancer Research

United Kingdom

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About

James O'Connor is a Professor and Team Leader at The Institute of Cancer Research in the United Kingdom. His research primarily focuses on cancer imaging, particularly in the translation of PET and dynamic contrast-enhanced MRI technologies. His recent publications include studies on the development of reproducible biomarkers and the integration of advanced imaging methodologies to enhance treatment evaluation in various types of cancer.

Recent Grants

Grant: Close

BioProton: Biologically relevant dose for Proton Therapy Planning

Open Date: 2019-03-31

Close Date: 2024-03-31

Grant: Close

NCITA: National Cancer Imaging Translational Accelerator

Open Date: 2019-01-01

Close Date: 2023-12-01

Grant: Close

Translating MRI biomarkers for clinical decision making in lung cancer

Open Date: 2017-01-01

Close Date: 2021-12-01

Grant: Close

MRI measurement of tumour spatial heterogeneity: pharmacological biomarker discovery and assay development

Open Date: 2013-01-01

Close Date: 2016-12-31

Grant: Close

MRI measurement of tumour spatial heterogeneity: pharmacological biomarker discovery and assay development

Open Date: 2013-01-01

Close Date: 2016-12-31

James O'Connor

Research Interests

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Contact this professor

About

Recent Grants

Articles (24)

Translation of dynamic contrast-enhanced imaging onto a magnetic resonance-guided linear accelerator in patients with head and neck cancer

Incidental findings in volunteer imaging used to develop radiotherapy MRI workflows

Translation of PET radiotracers for cancer imaging: recommendations from the National Cancer Imaging Translational Accelerator (NCITA) consensus meeting

Mastering CT-based radiomic research in lung cancer: a practical guide from study design to critical appraisal

Measuring repeatability of dynamic contrast-enhanced MRI biomarkers improves evaluation of biological response to radiotherapy in lung cancer

Independent component analysis (ICA) applied to dynamic oxygen‐enhanced MRI (OE‐MRI) for robust functional lung imaging at 3 T

Tumour Size and Overall Survival in a Cohort of Patients with Unifocal Glioblastoma: A Uni- and Multivariable Prognostic Modelling and Resampling Study

Feasibility of dynamic T2*‐based oxygen‐enhanced lung MRI at 3T

Combined Oxygen-enhanced MRI and perfusion imaging detect hypoxia modification from banoxantrone and atovaquone and track their differential mechanisms of action

OSIPI: A Significant Step Towards Reproducible MR Biomarkers

The ISMRM Open Science Initiative for Perfusion Imaging (OSIPI): Results from the OSIPI–Dynamic Contrast-Enhanced challenge

Impact of intensity standardisation and ComBat batch size on clinical-radiomic prognostic models performance in a multi-centre study of patients with glioblastoma

Criteria for the translation of radiomics into clinically useful tests

First-in-Human Technique Translation of Oxygen-Enhanced MRI to an MR Linac System in Patients with Head and Neck Cancer

In Reply to Chowdhry et al.

Multi-Maintenance Olaparib Therapy in Relapsed, Germline BRCA1/2-Mutant High-Grade Serous Ovarian Cancer (MOLTO): A Phase II Trial

Early Therapeutic Interventions for Newly Diagnosed Glioblastoma: Rationale and Review of the Literature

Plasma Tie2 trajectories identify vascular response criteria for VEGF inhibitors across advanced biliary tract, colorectal and ovarian cancers

Bayesian methods provide a practical real-world evidence framework for evaluating the impact of changes in radiotherapy

Clinical translation of quantitative magnetic resonance imaging biomarkers – An overview and gap analysis of current practice

Habitat Imaging of Tumors Enables High Confidence Sub-Regional Assessment of Response to Therapy

Imaging hypoxia in endometrial cancer: How and why should it be done?

Intensity standardization of MRI prior to radiomic feature extraction for artificial intelligence research in glioma—a systematic review

Radiomic Features From Diffusion-Weighted MRI of Retroperitoneal Soft-Tissue Sarcomas Are Repeatable and Exhibit Change After Radiotherapy

Collaborators (27)

Gerben Borst

anna barnes

Ayse Latif

Philip Blower

Tony Ng

Radhouene Neji

Azadeh Abravan

Oliver Gurney-Champion

Sarah Needleman

Grazyna Lipowska-Bhalla

Andrew Scarsbrook

Peter Hoskin

Hitesh Mistry

Daniel McGowan

Kevin M. Brindle

Gordon Jayson

Jamie McClelland

Alan Mcwilliam

Marcel van Herk

Philippe Lambin

David Coope

Gary Cook

Isabella Fornacon-Wood

Ananya Choudhury

David Buckley

Caroline Dive

Julian Matthews

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