James R. McLaughlan

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Semi-autonomous non-invasive surgery: The "outside in" of molecular-targeted theranostics for cancer

Open Date: 2018-06-28

Close Date: 2021-06-27

Articles (10)

Year:

2023

Year:

2022

Purpose To perform a systematic review and meta‐analysis of published literature investigating the use of lung ultrasound (LUS) on COVID‐19 patients, in emergency point of care settings, and to determine its diagnostic value compared with lung computed tomography (LCT) diagnostic performance. Whilst using the real‐time polymerase chain reaction test as the ‘gold standard’. Methods Literature searches were performed on MEDLINE, Embase, Web of Science, and PubMed databases for eligible studies. The LUS and LCT pooled diagnostic performance were measured using DerSimonian–Laird random effect method. Result Out of a total of 158 studies, 16 met the eligibility criteria and were included in this review. The pooled sensitivity, specificity, positive and negative likelihood ratios were 86.9%, 62.4%, 2.4 and 0.19, respectively for LUS and 93.5%, 72.6%, 3.3 and 0.05, respectively for LCT. Conclusion The lung ultrasound (LUS) demonstrated acceptable sensitivity but poor specificity when used independently to diagnose COVID‐19 pneumonia patients in emergency departments, while the lung computed tomography showed higher performance. Thus, LUS can be used to supplement existing diagnostic tools and possibly for the triage of patients.

Year:

2022

Year:

2022

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2021

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2021

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2021

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2021

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2020

Year:

2020

Collaborators (4)

Stephen Evans

Professor of Physics

University of Leeds

UNITED KINGDOM
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Giovanni Pittiglio

Tenure Track Assistant Professor

Worcester Polytechnic Institute

UNITED STATES
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Steven Freear

University of Leeds

UNITED KINGDOM
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James Chandler

University of Leeds

UNITED KINGDOM
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