James Thomas Brenna

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Professor

University of Texas at Austin

United States

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About

James Thomas Brenna is a Professor at the University of Texas at Austin, USA. His research focuses on the biochemical properties and health benefits of fatty acids, evidenced by his recent articles on topics such as the antioxidative effects of alpha-linolenic acid, the role of omega-3 eicosapentaenoic acid in tumorigenesis, and the impact of feed additives on fatty acid concentrations in dairy products. Through his work, he aims to advance the understanding of nutritional biochemistry and neurocognitive development.

Recent Grants

Grant: Close

Docosahexaenoic Acid Production in Freshwaters

Open Date: 2014-10-01

Close Date: 2017-09-30

Grant: Close

Molecular mechanism of omega-3 response

Open Date: 2013-01-01

Close Date: 2018-12-31

Grant: Close

GCx(py)GCC-IRMS for Isotope Metabolomics

Open Date: 2010-08-01

Close Date: 2016-04-30

Grant: Close

GCx(py)GCC-IRMS for Isotope Metabolomics

Open Date: 2010-08-01

Close Date: 2015-04-30

Grant: Close

Branched Chain FA and Gut Development

Open Date: 2010-04-01

Close Date: 2013-03-31

Articles (28)

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2021

Collaborators (9)

Ye Shen

UNITED STATES

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Karen Litwa

Assistant Professor

East Carolina University Brody School of Medicine

UNITED STATES

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Dong Hao Wang

University of Texas at Austin

UNITED STATES

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Jeffrey Eells

Associate Professor

East Carolina University

UNITED STATES

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Simon Dyall

University of Roehampton

UNITED KINGDOM

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Jeff Volek

Professor

Ohio State University

UNITED STATES

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Brian P. Hermann

University of Texas at San Antonio

UNITED STATES

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Martin-Paul Agbaga

Assistant Professor of Research

University of Oklahoma Health Sciences Center

UNITED STATES

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Kaixiong Ye

Assistant Professor

University of Georgia

UNITED STATES

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James Thomas Brenna

Research Interests

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About

Recent Grants

Articles (28)

Bis-Allylic Deuterated Docosahexaenoic Acid-Esterified Phospholipids Resist In Vivo Peroxidation in Rat Brain

Leucine as a feed additive enhances the concentration of branched-chain fatty acids in cow's milk

Hook, Line, and Thinker: Seafood Nets Benefits for Neurocognitive Development

Antioxidative Action of Alpha-Linolenic Acid during Its Gastroprotective Effect in an Indomethacin-Induced Gastric Injury Model

Polymethylene-Interrupted, Omega-3 and Branched-Chain Fatty Acids and Stable 13C Values of Wild Gulf of Mexico Oysters (Crassostrea virginica) from the Texas Coast

Warming plants and cooling essential fatty acids

Ultra-High Dose Oral ω3 Eicosapentaenoic Acid (EPA), Docosahexaenoic Acid (DHA), or Oxidation-Resistant Deuterated DHA Block Tumorigenesis in a MYCN-Driven Neuroblastoma Model

Paternò–Büchi Reaction Mass Spectrometry Enables Positional Assignment of Polymethylene-Interrupted Double Bonds in Food-Derived Lipids

Analysis of Intact In Vivo Peroxidized Phospholipids from Bovine Retina via LC-MS/MS and GC-MS/MS Using Autoxidized Retina Reference Standards

Omega-3 Long-Chain Polyunsaturated Fatty Acids in Nonseafood and Estimated Intake in the USA: Quantitative Analysis by Covalent Adduct Chemical Ionization Mass Spectrometry

Liquid Chromatography Coupled to Isotope Ratio Mass Spectrometry Expanded to Include Organic Mobile Phases

Unsaturated Fatty Acid Synthesis Is Associated with Worse Survival and Is Differentially Regulated by MYCN and Tumor Suppressor microRNAs in Neuroblastoma

Higher ratio of plasma omega-6/omega-3 fatty acids is associated with greater risk of all-cause, cancer, and cardiovascular mortality: A population-based cohort study in UK Biobank

Higher ratio of plasma omega-6/omega-3 fatty acids is associated with greater risk of all-cause, cancer, and cardiovascular mortality: A population-based cohort study in UK Biobank

Fatty acid isomerism: analysis and selected biological functions

Arachidonic acid: reconciling the dichotomy of its oxidative cascade through specific deuteration

Docosahexaenoic Acid Stability in Ready-to-Use Therapeutic Food

Docosahexaenoic Acid Explains the Unexplained in Visual Transduction

Docosahexaenoic Acid Explains the Unexplained in Visual Transduction

Pharmacokinetics and metabolism in mouse retina of bis-allylic deuterated docosahexaenoic acid (D-DHA), a new dry AMD drug candidate

Neurodevelopment, nutrition and genetics. A contemporary retrospective on neurocognitive health on the occasion of the 100th anniversary of the National Institute of Nutrition, Hyderabad, India

Deuterated Arachidonic Acid Ameliorates Lipopolysaccharide-Induced Lung Damage in Mice

Genome-wide association study of fish oil supplementation on lipid traits in 81,246 individuals reveals new gene-diet interaction loci

Dietary Saturated Fats and Health: Are the U.S. Guidelines Evidence-Based?

Toward Quantitative Sequencing of Deuteration of Unsaturated Hydrocarbon Chains in Fatty Acids

Acyl-CoA synthetase 6 is required for brain docosahexaenoic acid retention and neuroprotection during aging

The aromatase inhibitor letrozole restores FADS2 function in ER+ MCF7 human breast cancer cells

Safety and Efficacy of Sodium and Potassium Arachidonic Acid Salts in the Young Pig

Collaborators (9)

Ye Shen

Karen Litwa

Dong Hao Wang

Jeffrey Eells

Simon Dyall

Jeff Volek

Brian P. Hermann

Martin-Paul Agbaga

Kaixiong Ye

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