Jamie Spangler

Has grant

Assistant Professor

Johns Hopkins University

United States

Research Interests

Explore related searches

Professors in United States Professors in Immunology Immunology professors in United States

Contact this professor

Get a free first email built on one of their papers, ready for you to edit and send yourself.

About

Jamie Spangler is an Assistant Professor at Johns Hopkins University, USA. His research primarily focuses on T cell-stimulating platform development, therapeutic innovation through engineered growth factor ligands and receptors, and antibody biotechnology. Recent articles highlight his work on site-specific antibody conjugates, antibody fusion proteins, and immunocytokines aimed at enhancing therapeutic efficacy in autoimmune diseases and cancer.

Recent Grants

Grant: Close

Immunotherapeutic cytokine/antibody fusion proteins to treat melanoma

Open Date: 2021-06-01

Close Date: 2024-05-31

Grant: Close

Modulating T cell homeostasis via structure-based engineering of IL-23 variants

Open Date: 2012-07-01

Close Date: 2015-06-01

Articles (19)

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Collaborators (4)

Francesca Grisoni

Eindhoven University of Technology

NETHERLANDS

View details

Jordan Green

Professor

Johns Hopkins University

UNITED STATES

View details

Koen de Bruin

Eindhoven University of Technology

NETHERLANDS

View details

Christian Agatemor

Assistant Professor

University of Miami

UNITED STATES

View details

ApplyKite TwinLearns as you apply

Make your next move.

Prepare your application

Review drafts before you send them.

Jamie Spangler

Research Interests

Explore related searches

Contact this professor

About

Recent Grants

Articles (19)

Emerging approaches for T cell-stimulating platform development

Engineering growth factor ligands and receptors for therapeutic innovation

Production of site-specific antibody conjugates using metabolic glycoengineering and novel Fc glycovariants

Mechanistic computational modeling of monospecific and bispecific antibodies targeting interleukin-6/8 receptors

Cytokine/Antibody Fusion Protein Design and Evaluation

Molecular Engineering of Interleukin-2 for Enhanced Therapeutic Activity in Autoimmune Diseases

Engineering Anticytokine Antibodies for Immune Modulation

Engineering the IL‐4/IL‐13 axis for targeted immune modulation

Bioengineered particles expand myelin-specific regulatory T cells and reverse autoreactivity in a mouse model of multiple sclerosis

Masking T cell engagers mitigates on-target off-tumor activity

Author Correction: Engineering cytokine therapeutics

Discovery of antibodies targeting multipass transmembrane proteins using a suspension cell-based evolutionary approach

Engineering cytokine therapeutics

Redirecting the specificity of tripartite motif containing-21 scaffolds using a novel discovery and design approach

An engineered immunocytokine with collagen affinity improves the tumor bioavailability, tolerability, and therapeutic efficacy of IL-2

A versatile design platform for glycoengineering therapeutic antibodies

Empowering gene delivery with protein engineering platforms

Poly(Beta-Amino Ester)s as High-Yield Transfection Reagents for Recombinant Protein Production

Joined at the hip: The role of light chain complementarity determining region 2 in antibody self-association

Collaborators (4)

Francesca Grisoni

Jordan Green

Koen de Bruin

Christian Agatemor

Make your next move.