Jan Dohnalek

Head

Institute of Physiology CAS

Czech Republic

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Jan Dohnalek is the Head of the Institute of Biotechnology CAS in the Czech Republic. His research areas include molecular biophysics, RNA interactions, and enzyme characterization, as evidenced by recent articles on topics such as nuclease activity in Stenotrophomonas maltophilia and experimental phasing procedures. Dohnalek's work contributes to advancements in understanding microbial and enzymatic functions, as well as improving methodologies in macromolecular crystallography.

Articles (10)

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2025

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2024

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2023

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2022

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2021

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2021

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2021

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2020

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2020

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2020

Collaborators (5)

Petr Novak

Charles University

CZECH REPUBLIC

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Tomáš Kovaľ

Institute of Biotechnology of the Czech Academy of Sciences

CZECH REPUBLIC

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Petr Kolenko

České Vysoké Učení Technické v Praze Fakulta Jaderná a Fyzikálně inženýrská

CZECH REPUBLIC

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Kristýna Adámková

Institute of Biotechnology

CZECH REPUBLIC

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Mark Williams

UNITED KINGDOM

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Jan Dohnalek

Research Interests

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About

Articles (10)

Molecular Biophysics Database (MBDB) makes raw measurements findable and reusable

Substrate preference, <scp>RNA</scp> binding and active site versatility of <i>Stenotrophomonas maltophilia</i> nuclease <scp>S</scp>m<scp>N</scp>uc1, explained by a structural study

A highly active S1‐P1 nuclease from the opportunistic pathogen <i>Stenotrophomonas maltophilia</i> cleaves c‐di‐GMP

Atomic resolution studies of S1 nuclease complexes reveal details of RNA interaction with the enzyme despite multiple lattice-translocation defects

Chitinase Chit62J4 Essential for Chitin Processing by Human Microbiome Bacterium <i>Clostridium paraputrificum</i> J4

SHELIXIR: automation of experimental phasing procedures using SHELXC/D/E

PAIREF: paired refinement also for Phenix users

Kilohertz Macromolecular Crystallography Using an EIGER Detector at Low X-ray Fluxes

Demonstration of electron diffraction from membrane protein crystals grown in a lipidic mesophase after lamella preparation by focused ion beam milling at cryogenic temperatures

Paired refinement under the control of PAIREF

Collaborators (5)

Petr Novak

Tomáš Kovaľ

Petr Kolenko

Kristýna Adámková

Mark Williams

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