Jan Kowalski

Head, Professor

Medical University of Silesia

Poland

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Jan Kowalski is a Head Professor at the Medical University of Silesia in Poland. His research primarily focuses on the effects of gene overexpression in mesenchymal stem cells, apoptosis, and neurogenesis in relation to various psychological and neurological disorders. Recent publications highlight his work on BCL and BDNF gene interactions, polymorphisms related to schizophrenia and major depressive disorder, and the cytoprotective roles of natural compounds in cellular models.

Articles (12)

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2024

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2021

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2021

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2021

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2020

Collaborators (4)

Marcin Sadłocha

assistant professor, PhD MD

Medical University of Silesia

POLAND

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Rafal Stojko

Medical University of Silesia

POLAND

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Krzysztof Kucia

Head of the Department, Professor

Medical University of Silesia School of Medicine in Katowice

POLAND

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Patryk Rodek

Medical University of Silesia

POLAND

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Jan Kowalski

Research Interests

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Articles (12)

Roles of amygdalin and celastrol on staurosporine-treated mesenchymal stem cells in an in vitro culture

Effects of the Co-Overexpression of the BCL and BDNF Genes on the Gamma-Aminobutyric Acid-Ergic Differentiation of Wharton’s-Jelly-Derived Mesenchymal Stem Cells

Association study of the SLC1A2 (rs4354668), SLC6A9 (rs2486001), and SLC6A5 (rs2000959) polymorphisms in major depressive disorder.

Celastrol with a knockdown of miR-9-2, miR-17 and miR-19 causes cell cycle changes and induces apoptosis and autophagy in glioblastoma multiforme cells.

HSPB1 gene variants and schizophrenia: a case-control study in a Polish population.

Study of the influence of NGF-β gene overexpression in human mesenchymal stem cells on the expression level of SOX1 and neural pathway genes.

Survival and neurogenesis-promoting effects of the co-overexpression of BCLXL and BDNF genes on Whartons Jelly-derived mesenchymal stem cells.

The combination of baicalin with knockdown of miR148a gene suppresses cell viability and proliferation and induces the apoptosis and autophagy of human glioblastoma multiforme T98G and U87MG cells.

An association study of the HSPA8 gene polymorphisms with schizophrenia in a Polish population.

Cytoprotective roles of epigallocatechin gallate and resveratrol on staurosporine-treated mesenchymal stem cells in in vitro culture.

Synergistic effect of the long-term overexpression of Bcl-2 and BDNF Lentiviral in cell protecting against death and generating TH positive and CHAT positive cells from MSC.

An analysis of five TrkB gene polymorphisms in schizophrenia and the interaction of its haplotype with rs6265 BDNF gene polymorphism.

Collaborators (4)

Marcin Sadłocha

Rafal Stojko

Krzysztof Kucia

Patryk Rodek

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