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Jan Skotheim

Assistant Professor

Stanford University

United States

Research Interests

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Professors in United States Professors in Cell Biology Cell Biology professors in United States

Articles (20)

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2026

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2024

Collaborators (9)

Anca Pasca

Assistant Professor

Stanford University School of Medicine

UNITED STATES

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Paul François

Professeur

Université de Montréal

CANADA

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Michael Bassik

Associate Professor

Stanford University

UNITED STATES

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Jarno Mäkelä

Assistant Professor

Aalto University

FINLAND

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Gustavo Quintas Glasner de Medeiros

Staff of Professorship for Multicellular Systems

ETH Zürich

SWITZERLAND

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Evgeny Zatulovskiy

Group leader

University of Cambridge

UNITED KINGDOM

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Christina Curtis

Professor of Medicine & Genetics

Stanford University

UNITED STATES

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Ioannis Sanidas

Principal Investigator

Massachusetts General Hospital

UNITED STATES

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Peter Jackson

Professor

Stanford University School of Medicine

UNITED STATES

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Jan Skotheim

Research Interests

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Articles (20)

The FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle

Cell size modulates SBF and Whi5 chromatin association to regulate the Start of the budding yeast cell cycle.

The proportional scaling of mRNA and ribosome concentrations controls eukaryotic cell growth

How small can a cell be?

Cell size modulates ferroptosis susceptibility

Cell size-dependent mRNA transcription drives proteome remodeling

A Fkh1/2 binding site array in the WHI5 promoter drives sub-scaling transcription.

Chromatin association promotes UBR5-mediated degradation of Rb.

Emerging Strategies to Inhibit the G1/S Transition for Cancer Therapy

Cell enlargement drives aging-associated proteome remodeling and shortens replicative lifespan.

Identification and inhibition of the Cyclin D Rb-docking interface that drives cell division.

The Product neutrality function defining genetic interactions emerges from mechanistic models of cell growth

The G1/S transition in mammalian stem cells in vivo is autonomously regulated by cell size

Defined human tri-lineage brain microtissues.

Somatic polyploidy supports biosynthesis and tissue function by increasing transcriptional output

Intracellular diffusion in the cytoplasm increases with cell size in fission yeast.

Genome concentration limits cell growth and modulates proteome composition in Escherichia coli

The G 1 -S transition is promoted by Rb degradation via the E3 ligase UBR5

Genome dilution by cell growth drives starvation-like proteome remodeling in mammalian and yeast cells

Whi5 hypo- and hyper-phosphorylation dynamics control cell-cycle entry and progression

Collaborators (9)

Anca Pasca

Paul François

Michael Bassik

Jarno Mäkelä

Gustavo Quintas Glasner de Medeiros

Evgeny Zatulovskiy

Christina Curtis

Ioannis Sanidas

Peter Jackson

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