Jan Van Den Abbeele

Full professor; Head of Trypanosoma Unit

Institute of Tropical Medicine Antwerp

Belgium

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Jan Van Den Abbeele is a Full Professor and Head of the Trypanosoma Unit at the Institute of Tropical Medicine Antwerp, Belgium. His research focuses on the interactions between Trypanosoma brucei and its tsetse fly host, examining aspects such as flagellar fusion and the impact of glycoproteins on transmission. Recent publications highlight his investigations into the evolutionary trade-offs in Trypanosoma brucei gambiense and the role of various protein families in parasite development.

Articles (8)

Year:

2024

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2022

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2021

Year:

2020

Collaborators (6)

Álvaro Acosta Serrano

Professor of Vector Biology

University of Notre Dame

UNITED STATES

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Robert, L. Mach

TU Wien

AUSTRIA

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Esben Lorentzen

Aarhus University

DENMARK

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Lee Haines

Associate Professor

University of Notre Dame

UNITED STATES

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Benoit Vanhollebeke

Université libre de Bruxelles

BELGIUM

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Benoit Stijlemans

Vrije Universiteit Brussel

BELGIUM

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Jan Van Den Abbeele

Research Interests

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Articles (8)

Split-Cre-mediated GFP expression as a permanent marker for flagellar fusion of Trypanosoma brucei in its tsetse fly host.

The Trypanosoma brucei MISP family of invariant proteins is co-expressed with BARP as triple helical bundle structures on the surface of salivary gland forms, but is dispensable for parasite development within the tsetse vector

A multi-adenylate cyclase regulator at the flagellar tip controls African trypanosome transmission

Heme-deficient metabolism and impaired cellular differentiation as an evolutionary trade-off for human infectivity in Trypanosoma brucei gambiense.

Targeting the tsetse-trypanosome interplay using genetically engineered Sodalis glossinidius.

Prevalence of Trypanosoma and Sodalis in wild populations of tsetse flies and their impact on sterile insect technique programmes for tsetse eradication.

Tsetse salivary glycoproteins are modified with paucimannosidic N-glycans, are recognised by C-type lectins and bind to trypanosomes.

Evaluation of the relative roles of the Tabanidae and Glossinidae in the transmission of trypanosomosis in drug resistance hotspots in Mozambique.

Collaborators (6)

Álvaro Acosta Serrano

Robert, L. Mach

Esben Lorentzen

Lee Haines

Benoit Vanhollebeke

Benoit Stijlemans

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