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Janne Tapio Backman

University of Helsinki

Finland

Research Interests

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Professors in Finland

Articles (29)

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Collaborators (23)

Klaus Olkkola

University of Helsinki

FINLAND

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Tomi Laurila

Full Professor

Aalto University

FINLAND

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Laura Saarukka

University of Helsinki

FINLAND

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Mikko Niemi

Professor

University of Helsinki

FINLAND

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Kim Blomqvist

University of Helsinki

FINLAND

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Aleksi Tornio

University of Helsinki

FINLAND

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Anssi Mykkänen

University of Helsinki

FINLAND

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Dorota Kaminska

University of California, Los Angeles

UNITED STATES

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Johanna Kujala

University of Helsinki

FINLAND

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Mika Kontro

Group Leader

University of Helsinki

FINLAND

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Eija Kalso

Professor

University of Helsinki

FINLAND

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Marie-Noëlle PALUDETTO

University of Helsinki

FINLAND

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Pertti Neuvonen

Professor (emer.), Researcher

University of Helsinki

FINLAND

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Jussi Pihlajamäki

University of Eastern Finland

FINLAND

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Anne Filppula

Åbo Akademi University

FINLAND

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Outi Lapatto‐Reiniluoto

FINLAND

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Juha Sinisalo

University of Helsinki

FINLAND

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Tuija Tapaninen

University of Helsinki

FINLAND

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Mia Sivén

University of Helsinki

FINLAND

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Tanja Ruokoranta

University of Helsinki

FINLAND

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Päivi Hirvensalo

University of Helsinki

FINLAND

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Pekka Rauhala

University of Helsinki

FINLAND

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Eeva Moilanen

Professor of Pharmacology

FINLAND

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Janne Tapio Backman

Research Interests

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Articles (29)

Identification of a Functional CYP2C8 Variant Allele that Alters Splicing, Reduces Protein Expression, and Increases Drug Exposure

Effects of Celecoxib and Etoricoxib on the Pharmacokinetics and Pharmacological Effects of Orally Administered Tramadol: A Randomised Controlled Trial

Repeated Intake of Grapefruit Juice Inhibits CYP2B6, CYP2C9, CYP2C19, and CYP3A4 while Lingonberry Powder Does Not Induce Major CYP Enzymes in Humans

Clinical pharmacology consultations and their implementation in clinical decision making

Toward a More accurate, Evidence-Based Classification of CYP Inhibitors

A Phenotyping Tool for Seven Cytochrome P450 Enzymes and Two Transporters: Application to Examine the Effects of Clopidogrel and Gemfibrozil

Identification of Genetic Variants Associated with Pravastatin and Pitavastatin Pharmacokinetics

Capillary Sampling Enables Venetoclax Concentration Measurement in Acute Myeloid Leukaemia Within Academic Multicentre Trial

Early-career pre-congress meetings

Challenging the young and shaping the growth of clinical pharmacology

Screening of 16 major drug glucuronides for time-dependent inhibition of nine drug-metabolizing CYP enzymes – detailed studies on CYP3A inhibitors

Ticagrelor Increases Exposure to the Breast Cancer Resistance Protein Substrate Rosuvastatin

Genome‐Wide Association Study of Atorvastatin Pharmacokinetics: Associations With SLCO1B1, UGT1A3, and LPP

Posaconazole‐ibrutinib interaction cannot be avoided by staggered dosing: How to optimize ibrutinib dose during posaconazole treatment

Influence of Intravenous S-Ketamine on the Pharmacokinetics of Oral Morphine in Healthy Volunteers

The effect of hydroxychloroquine on cholesterol synthesis depends on the profile of cholesterol metabolism. A controlled clinical study

A comprehensive pharmacogenomic study indicates roles for SLCO1B1, ABCG2 and SLCO2B1 in rosuvastatin pharmacokinetics

Introduction of an electrochemical point‐of‐care assay for quantitative determination of paracetamol in finger‐prick capillary whole blood samples

Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3Ain vitro

Drug‐related deaths in a university hospital: Comparison to previous decades

The effect of hydroxychloroquine on cholesterol metabolism in statin treated patients after myocardial infarction.

Systemic hypertonic saline enhances glymphatic spinal cord delivery of lumbar intrathecal morphine

Genomewide Association Study of Simvastatin Pharmacokinetics

Pharmacogenomics of celiprolol – evidence for a role of P‐glycoprotein and organic anion transporting polypeptide 1A2 in celiprolol pharmacokinetics

Translational aspects of cytochrome P450‐mediated drug–drug interactions: A case study with clopidogrel

Healthcare costs and mortality associated with serious fluoroquinolone‐related adverse reactions

Medicines, environment and clinical pharmacology

Performance of Plasma Coproporphyrin I and III as OATP1B1 Biomarkers in Humans

Rifampin Reduces the Plasma Concentrations of Oral and Intravenous Hydromorphone in Healthy Volunteers

Collaborators (23)

Klaus Olkkola

Tomi Laurila

Laura Saarukka

Mikko Niemi

Kim Blomqvist

Aleksi Tornio

Anssi Mykkänen

Dorota Kaminska

Johanna Kujala

Mika Kontro

Eija Kalso

Marie-Noëlle PALUDETTO

Pertti Neuvonen

Jussi Pihlajamäki

Anne Filppula

Outi Lapatto‐Reiniluoto

Juha Sinisalo

Tuija Tapaninen

Mia Sivén

Tanja Ruokoranta

Päivi Hirvensalo

Pekka Rauhala

Eeva Moilanen

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