Jason Gleghorn

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Assistant Professor

University of Delaware

United States

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Jason Gleghorn is an Assistant Professor at the University of Delaware, USA. His research focuses on advanced microphysiological systems, immunomodulation techniques using lipid nanoparticles, and the pathophysiology of congenital diaphragmatic hernia. He has contributed to the development of innovative methodologies for studying cell and vascular interactions in various biomedical applications.

Recent Grants

Grant: Close

CAREER: A new class of microfluidic ex vivo culture models to understand whole organ physiology and disease

Open Date: 2020-02-01

Close Date: 2025-01-31

Grant: Close

Mechanisms of sex differences in neonatal pulmonary oxygen toxicity

Open Date: 2019-07-01

Close Date: 2024-06-30

Grant: Close

Mechanical Control of Cell Proliferation and Branching Morphogenesis in the Embryonic Lung

Open Date: 2019-01-15

Close Date: 2023-12-31

Grant: Close

Arsenic-mediated fibrosis and developmental dysregulation in the fetal lung

Open Date: 2017-12-15

Close Date: 2020-11-30

Grant: Close

Pressure in lung development and congenital diaphragmatic hernia

Open Date: 2017-04-01

Close Date: 2022-03-31

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UNITED STATES

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Shawn Polson

Associate Professor

University of Delaware

UNITED STATES

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drew weissman

Professor

University of Pennsylvania

UNITED STATES

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Jeffry Fuhrmann

Professor

University of Delaware

UNITED STATES

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David D Dunigan

Research Professor

University of Nebraska - Lincoln

UNITED STATES

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Barbra Ferrell

University of Delaware

UNITED STATES

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Timo L.M. ten Hagen

Associate Professor

Erasmus MC

NETHERLANDS

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Jason Gleghorn

Research Interests

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About

Recent Grants

Articles (17)

Cytokine mRNA Delivery and Local Immunomodulation in the Placenta Using Lipid Nanoparticles

The nitrofen/bisdiamine murine model of congenital diaphragmatic hernia has a pulmonary hypertension vascular phenotype consistent with human CDH

Democratizing Organ‐On‐Chip Technologies With a Modular, Reusable, and Perfusion‐Ready Microphysiological System

A straightforward cell culture insert model to incorporate biochemical and biophysical stromal properties into transplacental transport studies

Stochastic to Deterministic: A Straightforward Approach to Create Serially Perfusable Multiscale Capillary Beds

Systematic development of ionizable lipid nanoparticles for placental mRNA delivery using a design of experiments approach

Zonal patterning of extracellular matrix and stromal cell populations along a perfusable cellular microchannel

Delivery and short-term maternal and fetal safety of vaginally administered PEG-PLGA nanoparticles

Connecting clinical, environmental, and genetic factors point to an essential role for vitamin A signaling in the pathogenesis of congenital diaphragmatic hernia

Sex-related external factors influence pulmonary vascular angiogenesis in a sex-dependent manner

Secretion of the disulphide bond generating catalyst QSOX1 from pancreatic tumour cells into the extracellular matrix: Association with extracellular vesicles and matrix proteins

An Updated Review on EPR-Based Solid Tumor Targeting Nanocarriers for Cancer Treatment

Towards an integrative view of virus phenotypes.

Defective mesothelium and limited physical space are drivers of dysregulated lung development in a genetic model of congenital diaphragmatic hernia

Targeted Gq-GPCR activation drives ER-dependent calcium oscillations in chondrocytes

Significant Unresolved Questions and Opportunities for Bioengineering in Understanding and Treating COVID-19 Disease Progression

Osmotic Gradients in Epithelial Acini Increase Mechanical Tension across E-cadherin, Drive Morphogenesis, and Maintain Homeostasis

Collaborators (12)

Yuanjun Shen

John DeLong

Emily Day

James Van Etten

Mohamad-Gabriel Alameh

Rachel Young

Shawn Polson

drew weissman

Jeffry Fuhrmann

David D Dunigan

Barbra Ferrell

Timo L.M. ten Hagen

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