Jason Locasale

Associate Professor

Duke University School of Medicine

United States

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Dr. Jason Locasale is an Associate Professor at Duke University School of Medicine in the United States. His research focuses on diet and cancer metabolism, metabolic activity quantitation, and the interplay of amino acid and nucleotide metabolism in human health. His recent publications explore topics such as metabolic adaptations to dietary restrictions and the epigenetic implications of histone modifications.

Articles (15)

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2024

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2022

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2021

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2021

Collaborators (9)

Nolan Kamitaki

Broad Institute

UNITED STATES

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Teresa Sanchez

Associate Professor

Weill Cornell Medicine

UNITED STATES

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Patrick Jouandin

FRANCE

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Fangchao Wei

Duke University

UNITED STATES

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Kathleen Watt

Karolinska Institutet

SWEDEN

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Norbert Perrimon

Adjunct Professor, FlyBase PI

Harvard University

UNITED STATES

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Ola Larsson

Karolinska University Hospital

SWEDEN

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Anirban Kundu

Research Assistant Professor

University of Arizona

UNITED STATES

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Habib Rezanejad

Assistant Professor

MacEwan University

CANADA

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Jason Locasale

Research Interests

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About

Articles (15)

Separation of reproductive decline from lifespan extension during methionine restriction.

Diet and Cancer Metabolism

Quantitation of metabolic activity from isotope tracing data using automated methodology

Histone butyrylation is a dietary link to epigenetics

Lysine metabolism at the nexus of crotonylation and tumor immunity

Nucleotide metabolism is linked to cysteine availability

Delineating a Role for Methionine Metabolism in Colorectal Cancer

Amino acid variability, tradeoffs and optimality in human diet

Diet and Exercise in Cancer Metabolism

Author Correction: Sestrin mediates detection of and adaptation to low-leucine diets in Drosophila

MNK2 deficiency potentiates β-cell regeneration via translational regulation

Sestrin mediates detection of and adaptation to low-leucine diets in Drosophila

Integrated Metabolic Profiling and Transcriptional Analysis Reveals Therapeutic Modalities for Targeting Rapidly Proliferating Breast Cancers

The TGF-β/HDAC7 axis suppresses TCA cycle metabolism in renal cancer

Cellular stress signaling activates type-I IFN response through FOXO3-regulated lamin posttranslational modification

Collaborators (9)

Nolan Kamitaki

Teresa Sanchez

Patrick Jouandin

Fangchao Wei

Kathleen Watt

Norbert Perrimon

Ola Larsson

Anirban Kundu

Habib Rezanejad

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