Jason Plemel

Assistant Professor

University of Alberta

Canada

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About

Jason Plemel is an Assistant Professor at the University of Alberta, Canada. His research focuses on the roles of microglia in neurological conditions such as Alzheimer's disease and multiple sclerosis, with recent publications investigating immune cell interactions and remyelination processes. He has contributed to the understanding of stress hematopoiesis and the implications of sex differences in immune response.

Articles (18)

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2024

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2024

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2024

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2023

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2023

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

Collaborators (10)

Shokrollah Elahi

Professor of Immunology

University of Alberta

CANADA

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Thomas Simmen

CANADA

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Antonio Luchicchi

Assistant Professor

VU University Medical Center

NETHERLANDS

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Jesse Jackson

CANADA

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Huah Shin Ng

Flinders University

AUSTRALIA

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Valerie Sim

Associate professor

University of Alberta

CANADA

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William Branton

University of Alberta

CANADA

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Troy Baldwin

Professor

University of Alberta

CANADA

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Kei Takahashi-Yamashiro

University of Alberta

CANADA

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Martin Zirngibl

Technical University of Munich

GERMANY

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Jason Plemel

Research Interests

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Articles (18)

Bipotential B-neutrophil progenitors are present in human and mouse bone marrow and emerge in the periphery upon stress hematopoiesis.

Alzheimer's disease associated isoforms of human CD33 distinctively modulate microglial cell responses in 5XFAD mice.

Micro-diffusely abnormal white matter: An early multiple sclerosis lesion phase with intensified myelin blistering.

Microglia and Multiple Sclerosis.

Editorial: Insights in non-neuronal cells: 2021.

Editorial: Insights in non-neuronal cells: 2021

Social isolation produces a sex- and brain region-specific alteration of microglia state.

Social isolation produces a sex- and brain region-specific alteration of microglia state

Enrichment of Adult Mouse Dorsal Root Ganglia Neuron Cultures by Immunopanning.

Sex differences in peripheral immune cell activation: Implications for pain and pain resolution

Microglia promote remyelination independent of their role in clearing myelin debris.

Editorial: Insights in non-neuronal cells: 2022.

Gasdermin D activation in oligodendrocytes and microglia drives inflammatory demyelination in progressive multiple sclerosis.

Central nervous system macrophages in progressive multiple sclerosis: relationship to neurodegeneration and therapeutics

Single-cell microglial transcriptomics during demyelination defines a microglial state required for lytic carcass clearance.

Single-cell microglial transcriptomics during demyelination defines a microglial state required for lytic carcass clearance

Sex differences in the inflammatory response of the mouse DRG and its connection to pain in experimental autoimmune encephalomyelitis.

Sex differences in the inflammatory response of the mouse DRG and its connection to pain in experimental autoimmune encephalomyelitis

Collaborators (10)

Shokrollah Elahi

Thomas Simmen

Antonio Luchicchi

Jesse Jackson

Huah Shin Ng

Valerie Sim

William Branton

Troy Baldwin

Kei Takahashi-Yamashiro

Martin Zirngibl

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