Jayne Raper

Professor

Hunter College

United States

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Professor Jayne Raper is a faculty member at Hunter College in the United States. Her research primarily focuses on the interplay between innate immune factors and their role in various parasitic infections, emphasizing the functionality of Apolipoproteins and their cation channel properties. Recent publications explore the mechanisms of immune response and pathogen recognition, contributing to the understanding of immune regulation in disease contexts.

Articles (7)

Year:

2021

Year:

2021

Year:

2021

Year:

2020

Year:

2020

Year:

2020

Year:

2020

Collaborators (3)

Stephen M. Beverley

Washington University School of Medicine

UNITED STATES

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Jyoti Pant

Adjunct Professor

Hunter College

UNITED STATES

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Joseph Giovinazzo

University of Colorado Anschutz Medical Campus

UNITED STATES

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Jayne Raper

Research Interests

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Articles (7)

Interplay of Trypanosome Lytic Factor and innate immune cells in the resolution of cutaneous Leishmania infection

Coiled-coil binding of the leucine zipper domains of APOL1 is necessary for the open cation channel conformation

Apolipoproteins L1-6 share key cation channel-regulating residues but have different membrane insertion and ion conductance properties

Cation channel conductance and pH gating of the innate immunity factor APOL1 is governed by pore lining residues within the C-terminal domain.

Apolipoprotein L-1 renal risk variants form active channels at the plasma membrane driving cytotoxicity.

Inducible Germline IgMs Bridge Trypanosome Lytic Factor Assembly and Parasite Recognition.

All You Ever Wanted to Know About APOL1 and TLFs and Did Not Dare Ask.

Collaborators (3)

Stephen M. Beverley

Jyoti Pant

Joseph Giovinazzo

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