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Jean-Charles Lambert

Head of research unit

INSERM

France

Research Interests

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Professors in France Professors in Biostatistics Biostatistics professors in France

Articles (20)

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2026

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2025

Collaborators (32)

Julius Popp

SWITZERLAND

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Matthias Schmid

Full professor / Director

University of Bonn

GERMANY

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Pau Pastor

Institut Català de la Salut

SPAIN

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Miguel Calero

Instituto de Salud Carlos III

SPAIN

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Julie Dumont

Professor in cell biology and molecular genetics

Université de Lille

FRANCE

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Natalie Marchant

University College London

UNITED KINGDOM

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Clive Holmes

University of Southampton

UNITED KINGDOM

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Donald Conrad

Chief & Associate Professor

Oregon Health & Science University

UNITED STATES

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Catherine SCHRAMM

University of Rouen

FRANCE

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Jesper Qvist Thomassen

Senior Scientist

Rigshospitalet

DENMARK

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Sonja Scholz

National Institute of Neurological Disorders and Stroke

UNITED STATES

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Aude Deydier

Institut Pasteur de Lille

FRANCE

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Federica Anastasi

Senior Researcher

VU medisch centrum

NETHERLANDS

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Richard Redon

INSERM

FRANCE

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Jordi Pérez-Tur

Coordinador Adjunto al Área Global Vida

Agencia Estatal Consejo Superior de Investigaciones Científicas

SPAIN

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Harald Hampel

Chief Medical Officer (CMO), Senior Vice President

Eisai Inc

UNITED STATES

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Ida Karlsson

Karolinska Institutet

SWEDEN

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Yann Le Guen

Stanford University

UNITED STATES

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Ewa Malecka-Wojciesko

Medical University of Lodz

POLAND

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Danielle Posthuma

University of Amsterdam

NETHERLANDS

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Carlo Maj

Head of Bioinformatics | Research Group Leader – Genetic Epidemiology

University of Marburg

GERMANY

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Jeroen van Rooij

Assistant professor

Erasmus University Rotterdam

NETHERLANDS

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Anais Baudot

Aix-Marseille University

FRANCE

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Sami Heikkinen

Research Director

University of Eastern Finland

FINLAND

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Peter Holmans

Professor of Biostatistics and Genetic Epidemiology

Cardiff University

UNITED KINGDOM

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Dan Rujescu

Head of Clinical Division of General Psychiatry

Medical University of Vienna

AUSTRIA

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Gael Nicolas

PUPH

University of Rouen

FRANCE

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D.P. Wightman

University of Amsterdam

NETHERLANDS

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Devrim Kilinc

Institut Pasteur de Lille

FRANCE

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Alfredo Ramirez

University of Texas Health Science Center at San Antonio

UNITED STATES

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Lutz Froelich

Head

Zentralinstitut für Seelische Gesundheit

GERMANY

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R. Nathan Spreng

McGill University

CANADA

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Jean-Charles Lambert

Research Interests

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Articles (20)

A repeat expansion in GOLGA8A is a major risk factor for atypical frontotemporal lobar degeneration with ubiquitin-positive inclusions.

APOE-stratified genome-wide association analyses provide insights into the genetic etiology of Alzheimers’s disease

PLCG2 downregulation impairs synaptic function and increases Alzheimer’s disease hallmarks in neuronal cultures

Consensus meta-analysis of genome-wide association studies for Alzheimer’s disease and related dementias

GWAS meta-analysis of cerebrospinal fluid Alzheimer's biomarkers reveals loci regulating lipids, brain volume and autophagy.

BIN1 gain-of-function in the presynaptic compartment leads to isoform-specific synaptotoxicity

Inflammatory stimulus enhances synaptic material uptake by adult APP microglia in a microfluidic neuron-microglia co-culture model.

First genome-wide association study reveals immune-mediated aetiopathology in idiopathic achalasia

Assessing the de novo paradigm in sporadic early-onset Alzheimer disease trios

Cortical microstructural integrity predicts an exploitation bias in older adulthood

Genetic Modifiers of ABCA1 Activity Interact with APOE Isoforms to Mediate Alzheimer's Disease Risk.

<i>APOE</i> and genetic risk variants influence Alzheimer's disease onset in carriers of an extra copy of <i>APP</i> , with and without Down syndrome

Transferability of European-derived Alzheimer’s disease polygenic risk scores across multiancestry populations

Machine learning in Alzheimer’s disease genetics

Benchmark of computational methods to detect digenism in sequencing data

Replication of blood DNA methylomic signatures associated with cerebrospinal fluid levels of YKL-40 and NfL biomarkers.

Domain mapping of disease mutations reveals pathogenic SORL1 variants in Alzheimer''s disease.

BIN1 and Alzheimer's disease: the tau connection.

Calpain and caspase regulate Aβ peptide production via cleavage of KINDLIN2 encoded by the AD-associated gene FERMT2.

Uncovering atrophy progression pattern and mechanisms in individuals at risk of Alzheimer's disease.

Collaborators (32)

Julius Popp

Matthias Schmid

Pau Pastor

Miguel Calero

Julie Dumont

Natalie Marchant

Clive Holmes

Donald Conrad

Catherine SCHRAMM

Jesper Qvist Thomassen

Sonja Scholz

Aude Deydier

Federica Anastasi

Richard Redon

Jordi Pérez-Tur

Harald Hampel

Ida Karlsson

Yann Le Guen

Ewa Malecka-Wojciesko

Danielle Posthuma

Carlo Maj

Jeroen van Rooij

Anais Baudot

Sami Heikkinen

Peter Holmans

Dan Rujescu

Gael Nicolas

D.P. Wightman

Devrim Kilinc

Alfredo Ramirez

Lutz Froelich

R. Nathan Spreng

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