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Jean-Pierre BAZUREAU

Professor Classe Exceptionnelle - PR CE

University Name

France

Has grant

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Research Interests

Pharmaceutical Chemistry

70%

Organic Chemistry

40%

Chemical Biology

50%

Natural Products Chemistry

40%

Heterocyclic Chemistry

40%

Bioactive Compound

30%

Ligand Design

30%

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Recent Grants

Grant: Close

CONCERTO Cancéropôle Grand Ouest

Open Date: 2018-01-01

Close Date: 2020-06-01

Grant: Close

FUI TRIAD

Open Date: 2014-09-01

Close Date: 2019-10-01

Grant: Close

ION CHANNEL NETWORK Cancéropôle Grand Ouest

Open Date: 2012-12-01

Close Date: 2014-12-01

Grant: Close

MICROTHERAPY "Marie Curie Industry-Academia Partnerships and Pathways" FP7 EEC

Open Date: 2011-01-01

Close Date: 2015-01-01

Grant: Close

FUI PHARMASEA

Open Date: 2010-09-01

Close Date: 2013-08-01

Articles11

Design and Synthesis of Novel N-Benzylidene Derivatives of 3-Amino-4-imino-3,5-dihydro-4H-chromeno[2,3-d]pyrimidine under Microwave, In Silico ADME Predictions, In Vitro Antitumoral Activities and In Vivo Toxicity

Article Link

Year:

2024

Active U11 Peptide Luminescent Gold Nanoclusters for Pancreatic Tumor Cell Targeting

Article Link

Year:

2023

Practical approach to N-benzyl derivatives of 2-amino-8-methoxy-4H-chromene-3-carbonitrile by reductive amination: Exploration of their effects against protein kinases and in silico ADME profiling

Article Link

Year:

2023

Encapsulation of (E)-N’-(1-(7-(Diethylamino)-2-oxo-2H-chromen-3 yl)ethylidene)benzohydrazide (7-diEAHC) in β-cyclodextrins: Optimized synthesis of 7-diEACH and in silico ADME profiling, physical stability, antioxidant properties of encapsulated 7-diEAHC and bioavailability in rats

Article Link

Year:

2022

Structure–Activity Relationship in the Leucettine Family of Kinase Inhibitors

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Year:

2021

Design and Microwave Synthesis of New (5Z) 5-Arylidene-2-thioxo-1,3-thiazolinidin-4-one and (5Z) 2-Amino-5-arylidene-1,3-thiazol-4(5H)-one as New Inhibitors of Protein Kinase DYRK1A

Article Link

Year:

2021

Efficiency and selectivity of ionic liquids in microwave‐assisted extraction of major lichen phenolic compounds: a scalable process with recycling of ionic liquids

Article Link

Year:

2021

THE FRANCO-BRAZILIAN NETWORK ON NATURAL PRODUCTS (FB2NP): A NEW NETWORK PROMOTING COOPERATION AND EXCHANGES IN NATURAL PRODUCTS RESEARCH

Article Link

Year:

2021

(E)-N'-(1-(3-oxo-3H-benzo[f]chromen-2-yl)ethylidene)benzohydrazide protecting rat heart tissues from isoproterenol toxicity: Evidence from in vitro and in vivo tests.

Article Link

Year:

2020

Abemaciclib, a Recent Novel FDA-Approved Small Molecule Inhibiting Cyclin-Dependant Kinase 4/6 for the Treatment of Metastatic Breast Cancer: A Mini-Review

Article Link

Year:

2020

Synthesis of New 2-Phenylamino-4H-chromene-3-carbonitrile Derivatives and Their Effects on Tumor Cell Lines and against Protein Kinases

Article Link

Year:

2020

Collaborators4

Olivier MIGNEN

Senior lecturer

FRANCE

Thierry Charlier

Professor

Université de Rennes 1

FRANCE

Ludovic Paquin

Université de Rennes 1

FRANCE

Raphael Grougnet

Université Paris Cité

FRANCE

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