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Jeffry Nyman

Professor

Vanderbilt University

United States

Research Interests

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About

Jeffry Nyman is a Professor at Vanderbilt University in the United States. His research focuses on the regulation of bone mass and quality, emphasizing the roles of biglycan, decorin, and various dietary impacts on bone fragility. He has contributed to the field through innovative studies involving in vivo assessments, Raman spectroscopy, and the influence of immune cells on fracture healing. His recent publications reflect a commitment to advancing the understanding of bone health and mechanical properties.

Articles (26)

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Collaborators (18)

Jaya Krishnan

Vanderbilt University Medical Center

UNITED STATES

Jeffry Nyman

Research Interests

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About

Articles (26)

Full Spectrum Raman Spectroscopy Combined With Deep Learning for Prediction of Tensile Mechanical Properties of Human Cortical Bone

Hypertension worsens bone loss and weakens bone in aged ovariectomized mice

Effect of Canagliflozin Pretreatment on the Efficacy of Insulin Therapy to Rescue Type 1 Diabetes-Related Bone Fragility in Male Mice

Hypertension promotes bone loss and fragility by favoring bone resorption in mouse models

Pivotal roles of biglycan and decorin in regulating bone mass, water retention, and bone toughness

Differences and Similarities in Cortical Bone of the Femur between Donors with and without Type 2 Diabetes.

Increased fatty acid availability improves the osteo-anabolic effects of intermittent parathyroid hormone (iPTH) in murine models.

Fabric-elasticity relationships of femoral head trabecular bone are similar in Type 2 diabetes and non-diabetic individuals.

Prediction of biomechanical properties of ex vivo human femoral cortical bone using Raman spectroscopy and machine learning algorithms.

Predicting fracture toughness of human cortical bone from donors with and without type 2 diabetes using Raman spectroscopy and machine learning.

Programmed cell death protein 1 (PD-1) blockade regulates skeletal remodeling in a sex- and age-dependent manner.

A myostatin inhibitory antibody combined with insulin, partially rescues the musculoskeletal phenotype of female insulin-deficient diabetic mice.

Obese-diabetic female Ksr2 knockout mice develop brittle bones near end of life.

Bone Fragility in High Fat Diet-induced Obesity is Partially Independent of Type 2 Diabetes in Mice

In Vivo Assessment of Bone Quality Without X-rays

Callus γδ T cells and microbe-induced intestinal Th17 cells improve fracture healing in mice

Effect of ribose incubation on physical, chemical, and mechanical properties of human cortical bone

Assessment of spatially offset Raman spectroscopy to detect differences in bone matrix quality

Sensitivity of the amide I band to matrix manipulation in bone: a Raman micro-spectroscopy and spatially offset Raman spectroscopy study

Mapping glycation and glycoxidation sites in collagen I of human cortical bone

Identifying Bone Matrix Impairments in a Mouse Model of Neurofibromatosis Type 1 (NF1) by Clinically Translatable Techniques

Sclerostin ablation prevents aortic valve stenosis in mice

Finite element analysis of bone mechanical properties using MRI-derived bound and pore water concentration maps.

Causative or associative: A critical review of the role of advanced glycation end-products in bone fragility.

Evaluation of early bilateral ovariectomy in mice as a model of left heart disease

Intraoperative use of impact microindentation to assess distal radius bone quality.

Collaborators (18)

Jaya Krishnan

Florent Elefteriou

Rekha Gautam

Rafay Ahmed

Mark D. Does

Rheinallt Jones

Rui Hua

Jacquelyn Pennings

Elizabeth Rendina-Ruedy

Evangelia Kalaitzoglou

Robert Bunn

Subhashis Pal

W. David Merryman

Wenhan Chang

Daniel Perrien

Jean Jiang

Rachelle Johnson

David Harrison

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