Jeong-Yun Choi

Professor

Sungkyunkwan University School of Medicine

South Korea

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Jeong-Yun Choi is a Professor at Sungkyunkwan University School of Medicine in South Korea. His research focuses on DNA repair mechanisms, particularly the functions of DNA polymerases in cellular responses to UV radiation and chemotherapy. Recent articles by Professor Choi explore the implications of POLH variants in cancer sensitivity, the effects of HEBP2 on drug sensitivity in breast cancer, and the role of phosphorylation in neurodegeneration.

Articles (7)

Year:

2025

Year:

2024

Year:

2023

Year:

2023

Year:

2021

Year:

2021

Year:

2020

Collaborators (4)

Yunjong Lee

Assistant Professor

Sungkyunkwan University

SOUTH KOREA

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Xiaobo Mao

Associate Professor

Johns Hopkins University School of Medicine

UNITED STATES

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JI HUN KIM

Sungkyunkwan University School of Medicine

SOUTH KOREA

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Hye-Yeon Hwang

Sungkyunkwan University

SOUTH KOREA

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Jeong-Yun Choi

Research Interests

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Articles (7)

Four germline POLH variants, including two found in skin tumors, impair DNA polymerase η function and cellular tolerance to UV radiation and cisplatin

HEBP2 affects sensitivity to cisplatin and BCNU but not to paclitaxel in MDA-MB-231 breast cancer cells

Identification of Three Human POLH Germline Variants Defective in Complementing the UV- and Cisplatin-Sensitivity of POLH-Deficient Cells

PARIS undergoes liquid–liquid phase separation and poly(ADP‐ribose)‐mediated solidification

Parkin interacting substrate phosphorylation by c-Abl drives dopaminergic neurodegeneration

Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation.

Three Human Pol ι Variants with Impaired Polymerase Activity Fail to Rescue H2O2 Sensitivity in POLI-Deficient Cells

Collaborators (4)

Yunjong Lee

Xiaobo Mao

JI HUN KIM

Hye-Yeon Hwang

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