Jerry Leung

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The University of British Columbia

Canada

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Recent Grants

Grant: Close

Enhancing Transfusable Platelets Using mRNA Therapy to Produce Exogenous Proteins

Open Date: 2020-09-01

Close Date: 2023-09-01

Grant: Close

Megakaryocyte Engineering to Create Designer Platelets

Open Date: 2019-05-01

Close Date: 2020-05-01

Articles (15)

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2025

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2021

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2021

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2021

Collaborators (11)

Christian Kastrup

Professor

Medical College of Wisconsin

UNITED STATES

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Woosuk Steve Hur

Research Assistant Professor

University of North Carolina at Chapel Hill

UNITED STATES

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Diego López

University of Utah

UNITED STATES

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Miffy Cheng

Assistant Professor

The University of British Columbia

CANADA

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Massimo Cau

The University of British Columbia

CANADA

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Jayesh A. Kulkarni

The University of British Columbia

CANADA

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Alisa Wolberg

Prof.

University of North Carolina at Chapel Hill

UNITED STATES

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Molly Meng Hua Sung

CANADA

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Katayoun Saatchi

The University of British Columbia

CANADA

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Sarah Hedtrich (nee Küchler)

The University of British Columbia

CANADA

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Lakmali Munasinghage Silva

Assistant Professor

Harvard School of Dental Medicine

UNITED STATES

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Jerry Leung

Research Interests

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Recent Grants

Articles (15)

Liposomal lipid nanoparticles for extrahepatic delivery of mRNA

Genetic engineering of transfusable platelets with mRNA-lipid nanoparticles is compatible with blood banking practices

RNA therapeutics to control fibrinolysis: review on applications in biology and medicine

Exploring mechanisms of lipid nanoparticle‐mucus interactions in healthy and cystic fibrosis conditions

Lipid nanoparticles and siRNA targeting plasminogen provide lasting inhibition of fibrinolysis in mouse and dog models of hemophilia A

Induction of Bleb Structures in Lipid Nanoparticle Formulations of mRNA Leads to Improved Transfection Potency

Genetically engineered transfusable platelets using mRNA lipid nanoparticles

Lipid Nanoparticle-Mediated Hit-and-Run Approaches Yield Efficient and Safe In Situ Gene Editing in Human Skin

Elimination of fibrin polymer formation or crosslinking, but not fibrinogen deficiency, is protective against diet‐induced obesity and associated pathologies

Hypofibrinogenemia with preserved hemostasis and protection from thrombosis in mice with an Fga truncation mutation

Suppression of fibrin(ogen)-driven pathologies in disease models through controlled knockdown by lipid nanoparticle delivery of siRNA

Aortic intimal resident macrophages are essential for maintenance of the non-thrombogenic intravascular state

Simultaneous, Single-Particle Measurements of Size and Loading Give Insights into the Structure of Drug-Delivery Nanoparticles

Fibrin is a critical regulator of neutrophil effector function at the oral mucosal barrier

Emerging gene therapies for enhancing the hemostatic potential of platelets

Collaborators (11)

Christian Kastrup

Woosuk Steve Hur

Diego López

Miffy Cheng

Massimo Cau

Jayesh A. Kulkarni

Alisa Wolberg

Molly Meng Hua Sung

Katayoun Saatchi

Sarah Hedtrich (nee Küchler)

Lakmali Munasinghage Silva

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