Jessica Breznik

Assistant Professor in Immunology

University of Guelph

Canada

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About

Jessica Breznik is an Assistant Professor in Immunology at the University of Guelph, Canada. Her research focuses on immune responses related to SARS-CoV-2 vaccination and infection, as well as the effects of prior viral exposures and comorbid conditions on immunity. Recent publications include studies on immune exhaustion, responses in vulnerable populations, and the impact of obesity on immune cell function.

Articles (10)

Year:

2025

Year:

2025

Year:

2025

Year:

2024

Year:

2024

We found that diet-induced obesity in female mice has tissue- and time-dependent effects on intestinal paracellular permeability as well as monocyte-derived and tissue-resident macrophage numbers, surface marker phenotype, and intracellular production of the cytokines IL-10 and TNF. These changes were not mediated by TNF.

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2022

Collaborators (4)

Matthew Miller

Associate Professor

McMaster University

CANADA

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Jonathan Bramson

McMaster University

CANADA

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Dawn M. E. Bowdish

McMaster University

CANADA

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Candice Quin

Lecturer

University of Aberdeen

UNITED KINGDOM

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Jessica Breznik

Research Interests

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Articles (10)

Author Correction: No evidence of immune exhaustion after repeated SARS-CoV-2 vaccination in vulnerable and healthy populations

No evidence of immune exhaustion after repeated SARS-CoV-2 vaccination in vulnerable and healthy populations

Minimal Impact of Prior Common Cold Coronavirus Exposure on Immune Responses to Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination or Infection Risk in Older Adults in Congregate Care

Neutrophil-mediated innate immune resistance to bacterial pneumonia is dependent on Tet2 function

Reassuring humoral and cellular immune responses to SARS-CoV-2 vaccination in participants with systemic sclerosis

Diet-induced obesity alters intestinal monocyte-derived and tissue-resident macrophages and increases intestinal permeability in female mice independent of tumor necrosis factor

Early humoral and cellular responses after bivalent SARS-CoV-2 mRNA-1273.214 vaccination in long-term care and retirement home residents in Ontario, Canada: An observational cohort study.

Early Omicron infection is associated with increased reinfection risk in older adults in long-term care and retirement facilities.

Comparison of three dosing intervals for the primary vaccination of the SARS-CoV-2 mRNA Vaccine (BNT162b2) on magnitude, neutralization capacity and durability of the humoral immune response in health care workers: A prospective cohort study

Cytomegalovirus Seropositivity in Older Adults Changes the T Cell Repertoire but Does Not Prevent Antibody or Cellular Responses to SARS-CoV-2 Vaccination

Collaborators (4)

Matthew Miller

Jonathan Bramson

Dawn M. E. Bowdish

Candice Quin

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