Jessica Lang

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Assistant Professor

University of Wisconsin-Madison

United States

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About

Jessica Lang is an Assistant Professor at the University of Wisconsin-Madison, USA. Her research focuses on cancer genetics and treatment responses, particularly in ovarian cancer and small cell carcinoma of the ovary. Recent works include studies on gene expression signatures related to tumor response and alternative splicing, as well as the implications of specific genetic alterations in cancer therapeutics.

Recent Grants

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Characterization of the role of super-enhancers in ovarian cancer treatment response

Open Date: 2019-08-01

Close Date: 2024-08-31

Articles (11)

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2025

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2025

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2025

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2025

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2022

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2021

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2021

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2020

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2020

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2020

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2020

Collaborators (3)

Sampath Rangasamy

Associate Professor -Research

Translational Genomics Research Institute

UNITED STATES

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Amit M. Oza

University Health Network

CANADA

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April M. Weissmiller

Middle Tennessee State University

UNITED STATES

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Jessica Lang

Research Interests

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About

Recent Grants

Articles (11)

Cell-intrinsic platinum response and associated genetic and gene expression signatures in ovarian cancer

Loss of SMARCA4 Leads to Intron Retention and Generation of Tumor-Associated Antigens in Small Cell Carcinoma of the Ovary, Hypercalcemic Type

MYC Regulates a DNA Repair Gene Expression Program in Small Cell Carcinoma of the Ovary, Hypercalcemic Type

Super-enhancers and efficacy of triptolide in small cell carcinoma of the ovary hypercalcemic type

The COX-2–PGE2 Pathway Promotes Tumor Evasion in Colorectal Adenomas

Improved methods for RNAseq-based alternative splicing analysis.

Local production of lactate, ribose phosphate, and amino acids within human triple-negative breast cancer.

Re-expression of SMARCA4/BRG1 in small cell carcinoma of ovary, hypercalcemic type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism.

The novel reversible LSD1 inhibitor SP-2577 promotes anti-tumor immunity in SWItch/Sucrose-NonFermentable (SWI/SNF) complex mutated ovarian cancer.

Small-Cell Carcinoma of the Ovary, Hypercalcemic Type-Genetics, New Treatment Targets, and Current Management Guidelines.

Prostaglandin E2 Induces miR675-5p to Promote Colorectal Tumor Metastasis via Modulation of p53 Expression

Collaborators (3)

Sampath Rangasamy

Amit M. Oza

April M. Weissmiller

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