Jessica Wagenseil

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Washington University in St. Louis

United States

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About

Jessica Wagenseil is a Professor at Washington University in Saint Louis, USA. Her research focuses on biomechanical metrics and extracellular matrix remodeling, emphasizing the implications on vascular health and diseases, particularly concerning aortic conditions and tendon mechanics. Recent articles highlight her work on various aspects of arterial mechanics, aging, and the impact of elastin on vascular integrity.

Recent Grants

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Extracellular matrix effects on biotransport in aortic disease

Open Date: 2019-07-01

Close Date: 2022-06-30

Articles (15)

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Collaborators (3)

Carmen Halabi

Assistant Professor

Washington University in Saint Louis School of Medicine

UNITED STATES

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Lori Setton

Professor

Washington University in St. Louis

UNITED STATES

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Karen Downs

Professor Emerita

University of Wisconsin-Madison

UNITED STATES

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Jessica Wagenseil

Research Interests

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About

Recent Grants

Articles (15)

Fascicular Elastin Impacts Tendon-Specific Ramp-to-Failure and Fatigue Mechanics

Different physiologic biomechanical metrics correlate with aortic diameter increases in normal maturation compared to aneurysm progression in mice

Restoration of extracellular matrix is key to extending life in a mouse model of medial arterial calcification

Transport across the thoracic aortic wall: implications for aneurysm pathobiology, diagnosis, and treatment

Age- and sex-specific biomechanics and extracellular matrix remodeling of the ascending aorta in a mouse model of severe Marfan syndrome

Constitutive Modeling of Mouse Arteries Suggests Changes in Directional Coupling and Extracellular Matrix Remodeling That Depend on Artery Type, Age, Sex, and Elastin Amounts

Changes in transmural mass transport correlate with ascending thoracic aortic aneurysm diameter in a fibulin-4 E57K knockin mouse model

Pentagalloyl Glucose (PGG) Prevents and Restores Mechanical Changes Caused by Elastic Fiber Fragmentation in the Mouse Ascending Aorta

The matrix reloaded – Addressing structural integrity of the aortic wall in aneurysmal disease

Elastin, arterial mechanics, and stenosis

Passive biaxial mechanical behavior of newborn mouse aorta with and without elastin

A multiphasic model for determination of water and solute transport across the arterial wall: effects of elastic fiber defects

Vascular Smooth Muscle Cell Subpopulations and Neointimal Formation in Mouse Models of Elastin Insufficiency

Severing umbilical ties

Captopril treatment during development alleviates mechanically induced aortic remodeling in newborn elastin knockout mice

Collaborators (3)

Carmen Halabi

Lori Setton

Karen Downs

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