Jia Sheng

Associate Professor 10 Months

University at Albany, State University of New York

United States

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About

Jia Sheng is an Associate Professor at the University at Albany, State University of New York, USA. His research focuses on chemical probes for RNA modifications, the pharmacology of natural products, and the development of nucleotide-based tools for controlling biological functions. Recent publications highlight advancements in transcriptome mapping, RNA–protein interactions, and the design of innovative DNA nanoswitches for therapeutic applications.

Articles (19)

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2025

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2021

Collaborators (4)

Arun Richard Chandrasekaran

University at Albany, State University of New York

UNITED STATES

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Ken Halvorsen

University at Albany, State University of New York

UNITED STATES

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Jibin Abraham Punnoose

Assistant Professor

State University of New York at New Paltz

UNITED STATES

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Alan Chen

Associate Professor

University at Albany, State University of New York

UNITED STATES

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Jia Sheng

Research Interests

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About

Articles (19)

Nature‐Inspired Chemical Probes for Labeling tRNAs Containing 2‐Thiouridine (s2U)

An Oxyprenylated Phenylpropanoid Pharmacologic Scaffold for SelU Inhibition

Designing Reversible Photoswitching Azobenzene-Modified Nucleotide for Controlling Biological Function

A Geranylated Natural Product Simamycin Disrupts the Allosteric Catalysis of tRNA-2-selenouridine Synthase SelU

Transcriptome-wide mapping of N3-methylcytidine modification at single-base resolution

Heavy Chalcogen Properties of Sulfur and Selenium Enhance Nucleic Acid-Based Therapeutics

The Plethora of RNA–Protein Interactions Model a Basis for RNA Therapies

Inosine-Induced Base Pairing Diversity during Reverse Transcription

Toehold clipping: A mechanism for remote control of DNA strand displacement

Development of Nitroso-Based Probes for Labeling and Regulation of RAS Proteins in Cancer Cells via Sequential Ene-Ligation and Oxime Condensation

Resolving altered base-pairing of RNA modifications with DNA nanoswitches

Design, Synthesis, and Characterization of a Novel 2′–5′-Linked Amikacin-Binding Aptamer: An Experimental and MD Simulation Study

Fluorescent Aptaswitch for Detection of Lead Ions

Probing the Substrate Requirements of the In Vitro Geranylation Activity of Selenouridine Synthase (SelU)

Fluorescent Platforms for RNA Chemical Biology Research

Novel efficacious microRNA-30c analogs reduce apolipoprotein B secretion in human hepatoma and primary hepatocyte cells

Fluorescence-Based Binding Characterization of Small Molecule Ligands Targeting CUG RNA Repeats

Structural and Binding Effects of Chemical Modifications on Thrombin Binding Aptamer (TBA)

The origin of translation

Collaborators (4)

Arun Richard Chandrasekaran

Ken Halvorsen

Jibin Abraham Punnoose

Alan Chen

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