Jiakai Hou

Research Assistant Professor

University of Houston

United States

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Jiakai Hou is a Research Assistant Professor at the University of Houston, USA. His research focuses on cancer immunotherapy, the role of lncRNAs in tumorigenesis, and immune responses related to tumor intrinsic factors. Recently, he has published articles exploring the implications of PPP2R1A mutations, the enhancement of T cell activity through PRMT5 inhibitors, and the integration of multi-omics analyses to identify viral host factors.

Articles (10)

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2025

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2024

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2024

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2023

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2023

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2022

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2022

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2021

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2021

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2021

Collaborators (7)

Baohua Sun

The University of Texas MD Anderson Cancer Center

UNITED STATES

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Yiwen Chen

The University of Texas MD Anderson Cancer Center

UNITED STATES

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Yanjun Wei

The University of Texas MD Anderson Cancer Center

UNITED STATES

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Ken Chen

The University of Texas MD Anderson Cancer Center

UNITED STATES

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Xiangdong Lv

Assistant Professor

UTHealth

UNITED STATES

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Linghua Wang

Associate Professor

The University of Texas MD Anderson Cancer Center

UNITED STATES

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Weiyi Peng

University of Houston

UNITED STATES

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Jiakai Hou

Research Interests

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Articles (10)

PPP2R1A mutations portend improved survival after cancer immunotherapy

Integrated multi-omics analyses identify anti-viral host factors and pathways controlling SARS-CoV-2 infection

MTA-cooperative PRMT5 inhibitors enhance T cell-mediated antitumor activity in MTAP-loss tumors.

Multiomics analyses reveal DARS1-AS1 /YBX1–controlled posttranscriptional circuits promoting glioblastoma tumorigenesis/radioresistance

CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer

Single-cell CRISPR immune screens reveal immunological roles of tumor intrinsic factors.

Inhibiting Type I Arginine Methyltransferase Activity Promotes T Cell-Mediated Antitumor Immune Responses.

Systematic functional interrogation of human pseudogenes using CRISPRi.

LIMITing tumours with an immunogenic lncRNA.

Integrating genome-wide CRISPR immune screen with multi-omic clinical data reveals distinct classes of tumor intrinsic immune regulators.

Collaborators (7)

Baohua Sun

Yiwen Chen

Yanjun Wei

Ken Chen

Xiangdong Lv

Linghua Wang

Weiyi Peng

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