Jinsoo Seo

Assistant Professor

Daegu Gyeongbuk Institute of Science and Technology

South Korea

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About

Dr. Jinsoo Seo is an Assistant Professor at the Daegu Gyeongbuk Institute of Science and Technology in South Korea. His research focuses on neurodegenerative diseases, with recent articles addressing topics such as the role of pelotas in ribosome-associated quality control, neural progenitor cell differentiation in Alzheimer's disease, and mechanisms underlying ApoE4-induced amyloid regulation. Dr. Seo's work contributes to understanding cerebrovascular clearance and neuroinflammation in the context of neurodegeneration.

Articles (20)

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2025

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2020

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SOUTH KOREA

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Harvard University

UNITED STATES

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KEA JOO LEE

Department Head

Korea Brain Research Institute

SOUTH KOREA

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Jinsoo Seo

Research Interests

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Articles (20)

Pelota-mediated ribosome-associated quality control counteracts aging and age-associated pathologies across species

Enhanced differentiation of neural progenitor cells in Alzheimer’s disease into vulnerable immature neurons

Imaging lipid rafts reveals the principle of ApoE4-induced Aβ upregulation in human neurons

Author Correction: ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells

Correction to: Gamma frequency entrainment attenuates amyloid load and modifies microglia (Nature, (2016), 540, 7632, (230-235), 10.1038/nature20587)

ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells

Trametinib activates endogenous neurogenesis and recovers neuropathology in a model of Alzheimer’s disease

A Cdk5-derived peptide inhibits Cdk5/p25 activity and improves neurodegenerative phenotypes

ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes

Lomerizine inhibits LPS-mediated neuroinflammation and tau hyperphosphorylation by modulating NLRP3, DYRK1A, and GSK3α/β

LRRTM3 regulates activity-dependent synchronization of synapse properties in topographically connected hippocampal neural circuits

Restoration of Cathepsin D Level via L-Serine Attenuates PPA-Induced Lysosomal Dysfunction in Neuronal Cells

The Perspectives of Early Diagnosis of Schizophrenia Through the Detection of Epigenomics-Based Biomarkers in iPSC-Derived Neurons.

Neuromyelitis optica (NMO)‐IgG‐driven organelle reorganization in human iPSC‐derived astrocytes

APOE4-carrying human astrocytes oversupply cholesterol to promote neuronal lipid raft expansion and Aβ generation.

Impact of Genetic Risk Factors for Alzheimer’s Disease on Brain Glucose Metabolism

A logical network-based drug-screening platform for Alzheimer’s disease representing pathological features of human brain organoids

PICALM Rescues Endocytic Defects Caused by the Alzheimer's Disease Risk Factor APOE4.

<i>C9orf72</i>-Associated Arginine-Rich Dipeptide Repeat Proteins Reduce the Number of Golgi Outposts and Dendritic Branches in Drosophila Neurons.

Regorafenib Regulates AD Pathology, Neuroinflammation, and Dendritic Spinogenesis in Cells and a Mouse Model of AD

Collaborators (10)

SUN AH PARK

Hyoung Tae Kim

Murim Choi

Jaewon Ko

Hyunbum Jeon

Priyanka Narayan

Soochul Park

Sung Bae Lee

Anjanet Loon, Tuyeras

KEA JOO LEE

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