Joana Silva

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Instituto Universitário de Ciências da Saúde

Portugal

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Recent Grants

Grant: Open

The Unique Biology of RNA granules in Stress and Alzheimer's disease brain pathology

Open Date: 2022-10-24

Close Date: 2028-10-23

Grant: Close

Detection of AD markers in blood samples

Open Date: 2022-10-01

Close Date: 2025-09-30

Grant: Close

Unmasking the role of Tau protein in adult brain homeostasis: a novel approach for new answers

Open Date: 2018-02-01

Close Date: 2019-01-01

Grant: Close

Tau Therapeutics in Down syndrome & Alzheimers disease synaptic pathologies.

Open Date: 2017-09-01

Close Date: 2018-01-01

Grant: Close

A novel modulator of AMPA receptors against Alzheimer's Disease pathology: the first in vivo evidence

Open Date: 2017-04-01

Close Date: 2019-03-01

Articles (9)

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2025

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2025

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2024

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2023

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2022

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2021

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2021

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2021

Year:

2021

Collaborators (2)

Luísa Pinto

PORTUGAL

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Carina Soares‐Cunha

PORTUGAL

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Joana Silva

Research Interests

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Recent Grants

Articles (9)

Integration of omics to explore novel disease pathways in Down Syndrome neurodegeneration – Focusing on integrated stress response

Pretreatment with dimethyl fumarate prevents chronic pain and its comorbidities via Nrf2 pathway in a rat model of neuropathic pain

Glial-restricted precursors stimulate endogenous cytogenesis and effectively recover emotional deficits in a model of cytogenesis ablation

A novel isolation method for spontaneously released extracellular vesicles from brain tissue and its implications for stress-driven brain pathology

Chronic pain causes Tau-mediated hippocampal pathology and memory deficits

Suppression of adult cytogenesis in the rat brain leads to sex-differentiated disruption of the HPA axis activity

Rab35 and glucocorticoids regulate APP and BACE1 trafficking to modulate Aβ production

Constitutive deficiency of the neurogenic hippocampal modulator AP2¿ promotes anxiety-like behavior and cumulative memory deficits in mice from juvenile to adult periods

Allosteric modulation of AMPA receptors counteracts Tau-related excitotoxic synaptic signaling and memory deficits in stress- and Aβ-evoked hippocampal pathology

Collaborators (2)

Luísa Pinto

Carina Soares‐Cunha

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