Joaquim M.S. Cabral

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Professor and Head of Department of Bioengineering

Universidade de Lisboa Instituto Superior Técnico

Portugal

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About

Joaquim M.S. Cabral is a Professor and Head of the Department of Bioengineering at Universidade Técnica de Lisboa Instituto Superior Técnico in Portugal. His research areas encompass cellular agriculture, induced pluripotent stem cells, and tissue engineering, particularly focusing on hypertrophic cardiomyopathy and applications in muscle repair. Recent publications include studies on 3D printing of plant-based materials and novel bioprocessing strategies for therapeutic cell manufacturing.

Recent Grants

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Engineering an innervated heart organoid the initial step for in vitro modulation of neuro-cardiac cross-talk

Open Date: 2023-02-15

Close Date: 2024-08-14

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Quality by design-centered platform for the manufacturing of CAR-engineered NK cells and extracellular vesicles for immunotherapy

Open Date: 2022-01-01

Close Date: 2024-12-31

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Exploiting the power of decellularized extracellular matrix to fabricate hierarchical biomimetic scaffolds to regenerate functional periodontal tissues<br>

Open Date: 2021-03-01

Close Date: 2024-02-29

Grant: Close

New technologies for Stem cell Manufacturing bioprocess monitoring and ARTificial intelligence-based modeling

Open Date: 2021-02-01

Close Date: 2024-01-31

Grant: Close

Organoid Engineering for Production of 3D Cardiovascular Microtissues from Human Induced Pluripotent Stem Cells for Cardiotoxicity Assays

Open Date: 2018-10-01

Close Date: 2022-09-30

Articles (19)

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2022

Collaborators (19)

João C. Silva

Universidade de Aveiro

PORTUGAL

Joaquim M.S. Cabral

Research Interests

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About

Recent Grants

Articles (19)

Bioactive Nanofibrous Scaffolds Incorporating Decellularized Cell-Derived Extracellular Matrix for Periodontal Tissue Engineering

Synergy between 3D-extruded electroconductive scaffolds and electrical stimulation to improve bone tissue engineering strategies

3D printing of plant-based fat inks towards manufacturing complex cellular agriculture products with fatty structures

Patient-derived induced pluripotent stem cells to study non-canonical splicing variants associated with Hypertrophic Cardiomyopathy

Generation of induced pluripotent stem cells from an individual with early onset and severe hypertrophic cardiomyopathy linked to MYBPC3: c.772G¿&gt;¿A mutation

Generation of induced pluripotent stem cell lines from two unrelated individuals with familial hypertrophic cardiomyopathy carrying MYBPC3 nonsense mutations

Dual production of human mesenchymal stromal cells and derived extracellular vesicles in a dissolvable microcarrier-based stirred culture system

Developmental Toxicity Studies: The Path towards Humanized 3D Stem Cell-Based Models

Novel Electroactive Mineralized Polyacrylonitrile/PEDOT:PSS Electrospun Nanofibers for Bone Repair Applications

Bioprocessing Considerations towards the Manufacturing of Therapeutic Skeletal and Smooth Muscle Cells

Optimized operation of a controlled stirred tank reactor system for the production of mesenchymal stromal cells and their extracellular vesicles

Enhanced Proliferative and Osteogenic Potential of Periodontal Ligament Stromal Cells

BEMSCA: A novel decision support tool applied to the optimal design of a large-scale human induced pluripotent stem cell expansion bioprocess

Developing a Cell-Microcarrier Tissue-Engineered Product for Muscle Repair Using a Bioreactor System

Human multilineage pro-epicardium/foregut organoids support the development of an epicardium/myocardium organoid

Cost-Effective Mechanical Aggregation of Cardiac Progenitors and Encapsulation in Matrigel Support Self-Organization in a Dynamic Culture Environment

Xeno-Free Integrated Platform for Robust Production of Cardiomyocyte Sheets from hiPSCs

Hypothermic Preservation of Adipose-Derived Mesenchymal Stromal Cells as a Viable Solution for the Storage and Distribution of Cell Therapy Products

Bioprocess Economic Modeling: Decision Support Tools for the Development of Stem Cell Therapy Products

Collaborators (19)

João C. Silva

Diogo Nogueira

Frederico Barbosa

Teresa Carvalho Gonçalves

Paula Faria

Sandra N. Pinto

Tiago Fernandes

Perpetua Pinto-do-Ó

Jorge Morgado

Ana C. Marques

Cláudia L. da Silva

Manuel Prieto

JOSE JOAO BALTAZAR MENDES

Maria Margarida Diogo

Fabio Fernandes

Marta S. Carvalho

Frederico Castelo Ferreira

Nuno Alves

Paula Laranjeira

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Generation of induced pluripotent stem cells from an individual with early onset and severe hypertrophic cardiomyopathy linked to MYBPC3: c.772G¿>¿A mutation