Joel Watts

Assistant Professor

University of Toronto

Canada

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Dr. Joel Watts is an Assistant Professor at the University of Toronto, Canada. His research focuses on prion biology and neurodegenerative diseases, with recent publications exploring topics such as α-synuclein fibril dynamics, prion strain propagation, and the role of Aβ aggregates in Alzheimer’s disease. His work aims to elucidate the molecular mechanisms underlying these complex biological processes.

Articles (12)

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2025

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2024

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2024

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2024

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2024

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2023

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2023

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2021

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2021

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2021

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2020

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2020

Collaborators (6)

SURACHAI SUPATTAPONE

Dartmouth College

UNITED STATES

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Robert Bandsma

Associate Professor

University of Toronto

CANADA

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Dustin Loren Almanza

University of Toronto

CANADA

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Gerold Schmitt-Ulms

University of Toronto

CANADA

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Alejandro Iván Ruiz Riquelme

Assistant Professor

Universidade de Santiago de Compostela

SPAIN

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Peter Kim

Associate Professor

University of Toronto

CANADA

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Joel Watts

Research Interests

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About

Articles (12)

Shedding light on the α-synuclein fibril fuzzy coat

Upregulated pexophagy limits the capacity of selective autophagy

The importance of prion research

α-Synuclein strain propagation is independent of cellular prion protein expression in a transgenic synucleinopathy mouse model

The molecular determinants of a universal prion acceptor

A single protective polymorphism in the prion protein blocks cross‐species prion replication in cultured cells

Genetically engineered cellular models of prion propagation

Aβ43 aggregates exhibit enhanced prion-like seeding activity in mice

The aminoglycoside G418 hinders de novo prion infection in cultured cells

The existence of Aβ strains and their potential for driving phenotypic heterogeneity in Alzheimer’s disease

Identification of a homology-independent linchpin domain controlling mouse and bank vole prion protein conversion

Cellular models for discovering prion disease therapeutics: Progress and challenges

Collaborators (6)

SURACHAI SUPATTAPONE

Robert Bandsma

Dustin Loren Almanza

Gerold Schmitt-Ulms

Alejandro Iván Ruiz Riquelme

Peter Kim

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