Joerg J. Moehrle

VP, Head of Translational Medicine

Switzerland

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Articles (10)

Year:

2024

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2024

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2022

Collaborators (5)

Louise Marquart

Senior Lecturer Biostatistics

University of Queensland

AUSTRALIA

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John Ward

Lecturer/Senior Lecturer

Loughborough University

UNITED KINGDOM

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Oluwaseun Francis Egbelowo

University of Texas at Austin

UNITED STATES

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Jeremy Burrows

VP, Head of Discovery

SWITZERLAND

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Susan Charman

MONASH UNIVERSITY

AUSTRALIA

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Joerg J. Moehrle

Research Interests

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Articles (10)

How long does it take to develop a new drug?

PBPK‐led assessment of antimalarial drugs as candidates for Covid‐19: Simulating concentrations at the site of action to inform repurposing strategies

Characterizing the Blood-Stage Antimalarial Activity of Tafenoquine in Healthy Volunteers Experimentally Infected with Plasmodium falciparum

Development and application of a PBPK modeling strategy to support antimalarial drug development

Using Cryopreserved Plasmodium falciparum Sporozoites in a Humanized Mouse Model to Study Early Malaria Infection Processes and Test Prophylactic Treatments

Moving seasonal malaria chemoprevention out of its geographical isolation

Predicting Optimal Antimalarial Drug Combinations from a Standardized Plasmodium falciparum Humanized Mouse Model

A pharmacokinetic–pharmacodynamic model for chemoprotective agents against malaria

New In Vitro Interaction-Parasite Reduction Ratio Assay for Early Derisk in Clinical Development of Antimalarial Combinations

Safety, Tolerability, and Parasite Clearance Kinetics in Controlled Human Malaria Infection after Direct Venous Inoculation of Plasmodium falciparum Sporozoites: A Model for Evaluating New Blood-Stage Antimalarial Drugs.

Collaborators (5)

Louise Marquart

John Ward

Oluwaseun Francis Egbelowo

Jeremy Burrows

Susan Charman

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