Johan Larsbrink

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Associate Professor

Chalmers University of Technology

Sweden

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Johan Larsbrink is an Associate Professor at Chalmers University of Technology in Sweden. His research focuses on enzymatic processes in biomass conversion, including the structural and biochemical analysis of specific glycoside hydrolases and enzyme activity determinants in various microorganisms. Recent publications highlight his work on xylanases from Blastobotrys yeasts and the molecular mechanisms of polysaccharide degradation in fungi and bacteria.

Recent Grants

Grant: Open

Enzymatic modification of resin acids

Open Date: 2023-03-01

Close Date: 2027-02-01

Grant: Close

Circular bioeconomy development via network establishment between Chalmers and Brazilian Biorenewables National Laboratory

Open Date: 2023-01-01

Close Date: 2023-12-01

Grant: Close

Kartläggning av mikroorganismers nedbrytning av bark

Open Date: 2022-01-01

Close Date: 2024-12-01

Grant: Close

Towards complete cleavage of lignin-carbohydrate bonds

Open Date: 2022-01-01

Close Date: 2024-12-01

Grant: Close

A flexible bacterial consolidated bioprocess for conversion of plant biomass into short-chain fatty acids

Open Date: 2022-01-01

Close Date: 2025-12-01

Johan Larsbrink

Research Interests

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About

Recent Grants

Articles (21)

Genomic and secretomic analyses of Blastobotrys yeasts reveal key xylanases for biomass decomposition

Structural and biochemical basis for activity of Aspergillus nidulans α-1,3-glucanases from glycoside hydrolase family 71

Analyses of long-term fungal degradation of spruce bark reveals varying potential for catabolism of polysaccharides and extractive compounds

Exploration of three Dyadobacter fermentans enzymes uncovers molecular activity determinants in CE15

Streptomyces castrisilvae sp. nov. and Streptomyces glycanivorans sp. nov., novel soil streptomycetes metabolizing mutan and alternan

A unique metabolic gene cluster regulates lactose and galactose metabolism in the yeast Candida intermedia

Polysaccharide utilization loci from Bacteroidota encode CE15 enzymes with possible roles in cleaving pectin-lignin bonds

Boosting Enzyme Activity in Biomass Conversion by Modulating the Hydrolysis Process of Cellobiohydrolases

Structure‐based clustering and mutagenesis of bacterial tannases reveals the importance and diversity of active site‐capping domains

Genomic mining of Geobacillus stearothermophilus GF16 for xylose production from hemicellulose-rich biomasses using secreted enzymes

A unique AA5 alcohol oxidase fused with a catalytically inactive CE3 domain from the bacterium Burkholderia pseudomallei

Yeasts Have Evolved Divergent Enzyme Strategies To Deconstruct and Metabolize Xylan

Structural and functional investigation of a fungal member of carbohydrate esterase family 15 with potential specificity for rare xylans

Glucuronoyl esterases – enzymes to decouple lignin and carbohydrates and enable better utilization of renewable plant biomass

Resin acids play key roles in shaping microbial communities during degradation of spruce bark

Mechanism and biomass association of glucuronoyl esterase: an α/β hydrolase with potential in biomass conversion

Structural diversity and substrate preferences of three tannase enzymes encoded by the anaerobic bacterium Clostridium butyricum

Investigation and Alteration of Organic Acid Synthesis Pathways in the Mammalian Gut Symbiont Bacteroides thetaiotaomicron

Polysaccharide degradation by the Bacteroidetes — mechanisms and nomenclature

Structural and Functional Analysis of a Multimodular Hyperthermostable Xylanase-Glucuronoyl Esterase from Caldicellulosiruptor kristjansonii

A polysaccharide utilization locus from the gut bacterium Dysgonomonas mossii encodes functionally distinct carbohydrate esterases

Collaborators (14)

Caroline Simões Pereira

Sabina Leanti La Rosa

Bjørge Westereng

Lisbeth Olsson

Aleksej Zelezniak

Lauren S. McKee

Phil Pope

Leila Lo Leggio

Zhiyou Zong

Chunlin Xu

Eduard Kerkhoven

Anna Sundberg

Vincent Lombard

Cecilia Geijer

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