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Johan Spetz

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Researcher

University of Gothenburg

Sweden

Research Interests

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Professors in Sweden Professors in Biochemistry Biochemistry professors in Sweden

Recent Grants

Grant: Close

Utnyttjande av brister i celldödssignalvägar för att förutsäga och förbättra immunsvar mot huvud- och halscancer

Open Date: 2024-06-01

Close Date: 2025-06-01

Grant: Open

Mechanisms and prevention of radiation-induced heart inflammation

Open Date: 2023-06-01

Close Date: 2027-09-01

Grant: Close

Exploiting cell death pathway deficiencies to predict and enhance anti-cancer immune responses

Open Date: 2023-01-01

Close Date: 2025-01-01

Grant: Close

Apoptotic priming of vascular cells across tissues and lifespan predisposes them to cancer therapy-induced toxicities

Open Date: 2022-05-01

Close Date: 2022-05-01

Grant: Close

Dynamic regulation of apoptosis as a driver of cardiovascular disease caused by environmental lead exposure

Open Date: 2019-06-01

Close Date: 2024-06-01

Articles (17)

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2026

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2023

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2023

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2023

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2023

Collaborators (12)

Bengt Hallberg

Prof

University of Gothenburg

SWEDEN

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Eva Forssell-Aronsson

Senior medical physicist (1:e sjukhusfysiker)

Sahlgrenska universitetssjukhuset

SWEDEN

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Michelle A. Rudek

Professor

Johns Hopkins University

UNITED STATES

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Emily Robitschek

Stanford University

UNITED STATES

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Anikó Kovács

University of Gothenburg

SWEDEN

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Nathalie Agar

Principal Investigator

Brigham and Women's Hospital

UNITED STATES

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Xingping Qin

Harvard University

UNITED STATES

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Debattama Sen

Principal Investigator

Massachusetts General Hospital

UNITED STATES

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Veronica Rendo

Uppsala University

SWEDEN

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William Kim

Assistant Professor

Yale University

UNITED STATES

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Arnab Chakravarti

Chair and Professor

Ohio State University

UNITED STATES

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Magnus Gram

Senior Lecturer

Lund University

SWEDEN

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Johan Spetz

Research Interests

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Recent Grants

Articles (17)

Platelet aging and desialylation increase apoptotic priming and BCL-XL dependence

Advances in Somatostatin Receptor-Targeting Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumors: Biological Rationale, Combination Strategies, and Clinical Perspectives

Profiling proteomic responses in small intestinal neuroendocrine tumor GOT1 after [177Lu]Lu-DOTATATE therapy

A window-of-opportunity trial reveals mechanisms of response and resistance to navtemadlin in patients with recurrent glioblastoma

Evaluation of coadministration schedules of rA1M for kidney protection after administration of 177Lu-octreotide

Late apoptotic effects after treatment with 177 Lu-octreotate in small-intestine neuroendocrine GOT1 tumor model

Early proteomic response in thyroid gland after 131I administration in female Balb/c mice

Short and long-term effects on the thyroid proteome after 131I exposure

Synergistic Antitumor Effects of <sup>177</sup>Lu-Octreotide Combined with an ALK Inhibitor in a High-Risk Neuroblastoma Xenograft Model

Surgical window of opportunity trial reveals mechanisms of response and resistance to navtemadlin (KRT-232) in patients with recurrent glioblastoma

Late Age- and Dose-Related Effects on the Proteome of Thyroid Tissue in Rats after 131I Exposure

Comparison of 177Lu-octreotate and 177Lu-octreotide for treatment in human neuroblastoma-bearing mice

Late Age- and Dose-Related Effects on the Proteome of Thyroid Tissue in Rats after <sup>131</sup>I Exposure

Targeting TBK1 to overcome resistance to cancer immunotherapy

Apoptosis Inducing Agent 1 enhances cancer therapy-induced apoptosis by direct interaction with BAX and BAK

Cancer sensitivity to therapy is constrained by apoptosis regulation in cells of origin

Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX

Collaborators (12)

Bengt Hallberg

Eva Forssell-Aronsson

Michelle A. Rudek

Emily Robitschek

Anikó Kovács

Nathalie Agar

Xingping Qin

Debattama Sen

Veronica Rendo

William Kim

Arnab Chakravarti

Magnus Gram

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